2-Methylpyrazine
Based on 1 Customer Validation
2-Methylpyrazine is a flavoring agent and also a green solvent used in the preparation of non-solvent induced phase separation membranes.
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- Pureza: 99.98%
- No. CAS: 109-08-0
- Fòrmula: C5H6N2
- Peso molecular:94.12
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Almacenamiento:
RT, stored under nitrogen.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
2-Methylpyrazine serves as a green solvent for the preparation of polyethersulfone ultrafiltration membranes via the non-solvent induced phase separation method[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 109-08-0
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Appearance Liquid (Density: 1.03 g/cm3 )
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Peso molecular 94.12
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Fòrmula C5H6N2
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Color Colorless to light yellow
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SMILES
CC1=NC=CN=C1
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
RT, stored under nitrogen
In solvent -80°C 1 year -20°C 6 months
Solvente y solubilidad
DMSO : 100 mg/mL (1062.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (26.56 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (26.56 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureza y Documentación
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Ficha de datos (275 KB)
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SDS (604 KB)
- English - EN (604 KB)
- Français - FR (604 KB)
- Deutsch - DE (604 KB)
- Norwegian - NO (604 KB)
- Español - ES (604 KB)
- Swedish - SV (604 KB)
- Italian - IT (604 KB)
- Korean - KR (604 KB)
- Portuguese - PT (604 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 10.6247 mL | 53.1237 mL | 106.2473 mL | 265.6184 mL |
| 5 mM | 2.1249 mL | 10.6247 mL | 21.2495 mL | 53.1237 mL | |
| 10 mM | 1.0625 mL | 5.3124 mL | 10.6247 mL | 26.5618 mL | |
| 15 mM | 0.7083 mL | 3.5416 mL | 7.0832 mL | 17.7079 mL | |
| 20 mM | 0.5312 mL | 2.6562 mL | 5.3124 mL | 13.2809 mL | |
| 25 mM | 0.4250 mL | 2.1249 mL | 4.2499 mL | 10.6247 mL | |
| 30 mM | 0.3542 mL | 1.7708 mL | 3.5416 mL | 8.8539 mL | |
| 40 mM | 0.2656 mL | 1.3281 mL | 2.6562 mL | 6.6405 mL | |
| 50 mM | 0.2125 mL | 1.0625 mL | 2.1249 mL | 5.3124 mL | |
| 60 mM | 0.1771 mL | 0.8854 mL | 1.7708 mL | 4.4270 mL | |
| 80 mM | 0.1328 mL | 0.6640 mL | 1.3281 mL | 3.3202 mL | |
| 100 mM | 0.1062 mL | 0.5312 mL | 1.0625 mL | 2.6562 mL |
2-Methylpyrazine Related Classifications
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