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Referencia número: HY-112699

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AMPA receptor modulator-1

AMPA receptor modulator-1 is a potent, orally active and selective AMPAR regulatory protein TARP γ-8 negative modulator with a pIC₅₀ of 9.7, more selective over GluA1/γ-2 (pIC₅₀=5).

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No. CAS: 2036074-41-4
Fòrmula: C₁₆H₁₁ClF₃NO₂
Peso molecular:341.71

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

AMPA receptor modulator-1 Chemical Structure

No. CAS: 2036074-41-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- IC₅₀ & Target
Chemical Information
Pureza y Documentación
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Actividad biológica

Descripciòn

AMPA receptor modulator-1 is a potent, orally active and selective AMPAR regulatory protein TARP γ-8 negative modulator with a pIC₅₀ of 9.7, more selective over GluA1/γ-2 (pIC₅₀=5)^[1].

IC₅₀ & Target

pIC50: 9.7 (TARP γ-8)^[1]

Ver todos los productos específicos de isoformas iGluR :

Chemical Information

No. CAS 2036074-41-4
Peso molecular 341.71
Fòrmula C₁₆H₁₁ClF₃NO₂
SMILES

ClC1=C(C2=CC(C)=C(NC(C3)=O)C3=C2)C(OC(F)(F)F)=CC=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Ravula S, et al. Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8. ACS Med Chem Lett. 2018 Jul 13;9(8):821-826. [Content Brief]

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Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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AMPA receptor modulator-1

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Actividad biológica
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- IC₅₀ & Target
Chemical Information
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AMPA receptor modulator-1

Ver todos los productos específicos de isoformas iGluR

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

AMPA receptor modulator-1 Related Classifications

HY-112699 Related Classifications