AG 1406
Based on 1 Customer Validation
AG 1406 (compound M19) is a HER2 inhibitor, with an IC50 of 10.57 μM for HER2 in BT474 cell and >50 μM for EGFR in EGF-3T3 cell.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.03%
- No. CAS: 71308-34-4
- Fòrmula: C16H18N2O
- Peso molecular:254.33
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 71308-34-4
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Appearance Solid
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Peso molecular 254.33
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Fòrmula C16H18N2O
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Color Light yellow to yellow
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SMILES
N#C/C(C#N)=C/C1=CC(C(C)C)=C(O)C(C(C)C)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 100 mg/mL (393.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Pureza y Documentación
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Ficha de datos (268 KB)
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SDS (420 KB)
- English - EN (420 KB)
- Français - FR (420 KB)
- Deutsch - DE (420 KB)
- Norwegian - NO (420 KB)
- Español - ES (420 KB)
- Swedish - SV (420 KB)
- Italian - IT (420 KB)
- Korean - KR (420 KB)
- Portuguese - PT (420 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9319 mL | 19.6595 mL | 39.3190 mL | 98.2975 mL |
| 5 mM | 0.7864 mL | 3.9319 mL | 7.8638 mL | 19.6595 mL | |
| 10 mM | 0.3932 mL | 1.9659 mL | 3.9319 mL | 9.8297 mL | |
| 15 mM | 0.2621 mL | 1.3106 mL | 2.6213 mL | 6.5532 mL | |
| 20 mM | 0.1966 mL | 0.9830 mL | 1.9659 mL | 4.9149 mL | |
| 25 mM | 0.1573 mL | 0.7864 mL | 1.5728 mL | 3.9319 mL | |
| 30 mM | 0.1311 mL | 0.6553 mL | 1.3106 mL | 3.2766 mL | |
| 40 mM | 0.0983 mL | 0.4915 mL | 0.9830 mL | 2.4574 mL | |
| 50 mM | 0.0786 mL | 0.3932 mL | 0.7864 mL | 1.9659 mL | |
| 60 mM | 0.0655 mL | 0.3277 mL | 0.6553 mL | 1.6383 mL | |
| 80 mM | 0.0491 mL | 0.2457 mL | 0.4915 mL | 1.2287 mL | |
| 100 mM | 0.0393 mL | 0.1966 mL | 0.3932 mL | 0.9830 mL |
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