AR493
AR493 is an autophagy activator acting on AMPK (adenosine monophosphate-activated protein kinase). AR493 regulates pathways related to cellular energy sensing and increases autophagy levels. AR493 is promising for research of aging-associated diseases (such as diabetes, neurodegenerative diseases) and autophagy regulation.
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- No. CAS: 1290546-06-3
- Fòrmula: C16H17N3O5
- Peso molecular:331.32
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Ver todos los productos específicos de isoformas AMPK
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEL | CC50 |
>100 μM
Compound: 12d
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Cytotoxicity against human HEL cells assessed as reduction in cell viability measured after 3 days by beckman coulter counting method
Cytotoxicity against human HEL cells assessed as reduction in cell viability measured after 3 days by beckman coulter counting method
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[PMID: 33894564] |
| HEp-2 | CC50 |
>100 μM
Compound: 12d
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Cytotoxicity in human Hep2 cells assessed as reduction in cell viability measured after 3 days by beckman coulter counting method
Cytotoxicity in human Hep2 cells assessed as reduction in cell viability measured after 3 days by beckman coulter counting method
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[PMID: 33894564] |
| MDCK | CC50 |
>100 μM
Compound: 12d
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Cytotoxicity in dog MDCK cells assessed as reduction in cell viability measured after 3 days by beckman coulter counting method
Cytotoxicity in dog MDCK cells assessed as reduction in cell viability measured after 3 days by beckman coulter counting method
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[PMID: 33894564] |
| Vero | CC50 |
>100 μM
Compound: 12d
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Cytotoxicity in African green monkey Vero cells assessed as reduction in cell viability measured after 5 days by resazurin dye based assay
Cytotoxicity in African green monkey Vero cells assessed as reduction in cell viability measured after 5 days by resazurin dye based assay
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[PMID: 33894564] |
Chemical Information
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No. CAS 1290546-06-3
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Peso molecular 331.32
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Fòrmula C16H17N3O5
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SMILES
CN(C1=CC=CC=C1OC2=CN3[C@H]4C[C@H](O)[C@@H](CO)O4)C2=NC3=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AR493 Related Classifications
HY-174157 Related Classifications
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