BDM88855
BDM88855 is an allosteric inhibitor for the homolog AcrB protein. BDM88855 can boost the antibacterial effect of a panel of antibiotics (eg: Oxacillin (HY-B0925A), Linezolid (HY-10394), Novobiocin (HY-B0425), etc.) on wild-type E. coli.
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- No. CAS: 2892824-25-6
- Fòrmula: C13H14ClN3
- Peso molecular:247.72
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 2892824-25-6
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Peso molecular 247.72
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Fòrmula C13H14ClN3
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SMILES
ClC1=C(N2CCNCC2)N=C(C=CC=C3)C3=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Plé C, et al. Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps. Nat Commun. 2022 Jan 10;13(1):115. [Content Brief]
[2]. Bera A, et al. Exploring transmembrane allostery in the MexB: DB08385 variant as a promising inhibitor-like candidate against Pseudomonas aeruginosa antibiotic resistance: a computational study. Phys [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BDM88855 Related Classifications
HY-162595 Related Classifications
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