BMS-978299
BMS-978299 is an IRAK4 inhibitor that can be used for the study of immune disorders.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1610016-88-0
- Fòrmula: C21H24FN5O2S
- Peso molecular:429.51
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
[1]|
IRAK4 |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| PBMC | IC50 |
230 nM
Compound: 12
|
Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and measured after 5 hrs by ELISA
Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and measured after 5 hrs by ELISA
|
[PMID: 32676146] |
Chemical Information
-
No. CAS 1610016-88-0
-
Peso molecular 429.51
-
Fòrmula C21H24FN5O2S
-
SMILES
C(NC[C@H](C(C)(C)O)F)(=O)C=1C(NC2CC2)=CC(NC=3C=C4C(=CC3)N=CS4)=NC1
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BMS-978299 Related Classifications
HY-W900240 Related Classifications
Powered by Bioz