Chlortetracycline
Based on 7 publication(s) in Google Scholar
Chlortetracycline (7-Chlorotetracycline) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline is also a antibiotic that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline is a specific and potent calcium ionophore antibiotic, inhibiting binding of aminoacyl-tRNA to ribosomes.
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- No. CAS: 57-62-5
- Fòrmula: C22H23ClN2O8
- Peso molecular:478.88
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Publications Citing Use of MedChemExpress (MCE) Chlortetracycline
More- Food Chem X. 2026 Feb 8:34:103646. [Abstract]
- Antibiotics (Basel). 2026 Jan 6;15(1):62. [Abstract]
- Sci Rep. 2022 Aug 25;12(1):14502. [Abstract]
- Biology (Basel). 2025 Jun 24;14(7):755. [Abstract]
- Saudi Pharm J. 2021 Jun;29(6):566-575. [Abstract]
- BMC Vet Res. 2025 Jul 23;21(1):485. [Abstract]
- Chemosphere. 2019 Jun:225:378-387. [Abstract]
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Actividad biológica
Descripciòn
IC50 & Target
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Tetracycline |
In Vitro
Chlortetracycline (10, 50, 100, 200 mg/L, 18 days) inhibits methane (a main component of biogas) production and is degradated and metabolized by anaerobic digestion (AD) at high concentrations and incubation temperatures[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:SPF level Kunming mice (KM)[4]
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Dosage:50 mg/kg
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Administration:p.o., administration for 42 consecutive days
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Result:Significantly increased the IgM antibody levels, decreased the IgA antibody levels and not influence IgG antibody levels in serum of mice.
Chemical Information
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No. CAS 57-62-5
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Appearance Solid
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Peso molecular 478.88
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Fòrmula C22H23ClN2O8
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Color Light yellow to yellow
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SMILES
O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])[C@](C)(O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4Cl)N
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Synonyms
7-Chlorotetracycline
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (7)
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Journal Impact Factor
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Most Recent
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Food Chem X
Machine learning prioritization of antibiotic residues in aquatic foods reveals exposure-driven genotoxic risk mediated by BCL2. [Abstract]2026 Feb 8:34:103646. PMID: 41756597 -
Antibiotics (Basel)
In Vitro and In Vivo Evaluation of Nitroxoline as an Effective Antimicrobial Alternative to Poultry Production. [Abstract]2026 Jan 6;15(1):62. PMID: 41594099 -
Sci Rep
Qualitative immunoassay for the determination of tetracycline antibiotic residues in milk samples followed by a quantitative improved HPLC-DAD method. [Abstract]2022 Aug 25;12(1):14502. PMID: 36008564 -
Biology (Basel)
Polysaccharide Supplements from Millettia speciosa Champ. ex Benth Enhance Growth and Meat Quality in Wenchang Chickens. [Abstract]2025 Jun 24;14(7):755. PMID: 40723316 -
Saudi Pharm J
Determination of tetracycline, oxytetracycline and chlortetracycline residues in seafood products of Saudi Arabia using high performance liquid chromatography-Photo diode array detection. [Abstract]2021 Jun;29(6):566-575. PMID: 34194263 -
BMC Vet Res
Dietary supplementation of polysaccharides from Millettia speciosa Champ. ex Benth on growth performance, immune function, antioxidant abilities and intestinal health of Wenchang chickens. [Abstract]2025 Jul 23;21(1):485. PMID: 40702452 -
Chemosphere
Mass-balance-model-based evaluation of sewage treatment plant contribution to residual pharmaceuticals in environmental waters. [Abstract]2019 Jun:225:378-387. PMID: 30884299
Pureza y Documentación
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Ficha de datos (278 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
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- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Elmund GK, et al. Role of excreted chlortetracycline in modifying the decomposition process in feedlot waste. Bull Environ Contam Toxicol. 1971 Mar-Apr;6(2):129-32. [Content Brief]
[2]. Saling PM, et al. Mouse gamete interactions during fertilization in vitro. Chlortetracycline as a fluorescent probe for the mouse sperm acrosome reaction. J Cell Biol. 1979 Dec;83(3):544-55. [Content Brief]
[4]. Liu D, et al. Synthesis and evaluation of bisulfate/mesylate-conjugated chlortetracycline with high solubility and bioavailability[J]. Acta Pharm. 2020 Dec 1;70(4):483-498. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Chlortetracycline Related Classifications
HY-B1327A Related Classifications
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