CJ28
Based on 1 Customer Validation
CJ28 is a cortisol biosynthesis inhibitor that significantly inhibits basal and stimulated cortisol production in human adrenal carcinoma cell lines. CJ28 exhibits inhibitory effects by reducing steroidogenesis and de novo cholesterol biosynthesis.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.21%
- No. CAS: 3047118-54-4
- Fòrmula: C14H11BrN4O
- Peso molecular:331.17
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
Descripciòn
IC50 & Target
Cortisol biosynthesis[1]
Chemical Information
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No. CAS 3047118-54-4
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Appearance Solid
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Peso molecular 331.17
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Fòrmula C14H11BrN4O
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Color White to off-white
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SMILES
O=C(NC1=NC2=CC=CC=C2N1)NC3=CC(Br)=CC=C3
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 50 mg/mL (150.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0196 mL | 15.0980 mL | 30.1960 mL | 75.4899 mL |
| 5 mM | 0.6039 mL | 3.0196 mL | 6.0392 mL | 15.0980 mL | |
| 10 mM | 0.3020 mL | 1.5098 mL | 3.0196 mL | 7.5490 mL | |
| 15 mM | 0.2013 mL | 1.0065 mL | 2.0131 mL | 5.0327 mL | |
| 20 mM | 0.1510 mL | 0.7549 mL | 1.5098 mL | 3.7745 mL | |
| 25 mM | 0.1208 mL | 0.6039 mL | 1.2078 mL | 3.0196 mL | |
| 30 mM | 0.1007 mL | 0.5033 mL | 1.0065 mL | 2.5163 mL | |
| 40 mM | 0.0755 mL | 0.3774 mL | 0.7549 mL | 1.8872 mL | |
| 50 mM | 0.0604 mL | 0.3020 mL | 0.6039 mL | 1.5098 mL | |
| 60 mM | 0.0503 mL | 0.2516 mL | 0.5033 mL | 1.2582 mL | |
| 80 mM | 0.0377 mL | 0.1887 mL | 0.3774 mL | 0.9436 mL | |
| 100 mM | 0.0302 mL | 0.1510 mL | 0.3020 mL | 0.7549 mL |