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United States

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Referencia número: HY-153902

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DG-8

DG-8 is a potent inhibitor of STAT3-dependent transcription (IC₅₀ 0.98 μM). DG-8 is a fluorescent probe that contains a fluorescent dansyl moiety.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₂₇H₂₈Cl₃N₅O₄S
Peso molecular:624.97

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

DG-8 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

DG-8 is a potent inhibitor of STAT3-dependent transcription (IC₅₀ 0.98 μM). DG-8 is a fluorescent probe that contains a fluorescent dansyl moiety^[1].

Ver todos los productos específicos de isoformas STAT :

Chemical Information

Peso molecular 624.97
Fòrmula C₂₇H₂₈Cl₃N₅O₄S
SMILES

O=C(N(CCN(C)S(C1=C(C=CC=C2N(C)C)C2=CC=C1)(=O)=O)C)C3=CC=C(N4C(C(Cl)=C(Cl)C=N4)=O)C=C3.Cl
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Busker S, et al. Irreversible TrxR1 inhibitors block STAT3 activity and induce cancer cell death. Sci Adv. 2020 Mar 20;6(12):eaax7945. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Actividad biológica
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Chemical Information
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Referencias

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DG-8

Ver todos los productos específicos de isoformas STAT

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

DG-8 Related Classifications

HY-153902 Related Classifications