Digallic acid
Digallic acid is an antioxidant, antimutagenic, antigenotoxic, and anti-hyperuricemic compound. Digallic acid is a reverse transcriptase and XOD, URAT1 (IC50: 5.34 μM) inhibitor. Digallic acid scavenges DPPH· and O2·− radicals. Digallic acid induces apoptosis. Digallic acid can be isolated from the fruits of Pistascia lentiscus.
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- No. CAS: 536-08-3
- Fòrmula: C14H10O9
- Peso molecular:322.22
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Actividad biológica
Descripciòn
Chemical Information
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No. CAS 536-08-3
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Appearance Solid
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Peso molecular 322.22
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Fòrmula C14H10O9
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Color White to off-white
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SMILES
OC(C1=CC(OC(C2=CC(O)=C(C(O)=C2)O)=O)=C(C(O)=C1)O)=O
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Bhouri W, et al. Digallic acid from Pistascia lentiscus fruits induces apoptosis and enhances antioxidant activities. Phytother Res. 2012 Mar;26(3):387-91. [Content Brief]
[2]. Nakane H, et al. Differential inhibition of reverse transcriptase and various DNA polymerases by digallic acid and its derivatives. J Nat Prod. 1990 Sep-Oct;53(5):1234-40. [Content Brief]
[3]. Zheng F, et al. Discovery of digallic acid as XOD/URAT1 dual target inhibitor for the treatment of hyperuricemia. Bioorg Chem. 2024 Jun;147:107381. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)