Dopal (purity>80%)
Dopal (purity>80%) is a metabolite and aldehyde neurotoxin of Dopamine (HY-B0451). Dopal (purity>80%) exhibits cytotoxicity, induces α-synuclein oligomerization and aggregation, and is closely associated with the pathogenesis of Parkinson's disease. Dopal (purity>80%) can be used in research related to Parkinson's disease.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 5707-55-1
- Fòrmula: C8H8O3
- Peso molecular:152.15
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Ver todos los productos específicos de isoformas α-synuclein
More
Actividad biológica
Descripciòn
IC50 & Target
|
α-synuclein Aggregation |
Chemical Information
-
No. CAS 5707-55-1
-
Peso molecular 152.15
-
Fòrmula C8H8O3
-
SMILES
O=CCC1=CC=C(O)C(O)=C1
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Masato A, et al. DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson's disease. NPJ Parkinsons Dis. 2023 Mar 25;9(1):42. [Content Brief]
[2]. Bloch DN, et al. Scavenging neurotoxic aldehydes using lysine carbon dots. Nanoscale Adv. 2023 Jan 19;5(5):1356-1367. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)