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Referencia número: HY-135388

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ent-Ezetimibe

Name: ent-Ezetimibe
Brand: MedChemExpress
SKU: HY-135388
Price: 560.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: ent-SCH 58235)

Revisión del cliente

Based on 1 Customer Validation

ent-Ezetimibe (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 1376614-99-1
Fòrmula: C₂₄H₂₁F₂NO₃
Peso molecular:409.43

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

ent-Ezetimibe Chemical Structure

No. CAS: 1376614-99-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

HY-135391

Ezetimibe phenoxy glucuronide

Actividad biológica

Descripciòn

Chemical Information

No. CAS 1376614-99-1
Appearance Solid
Peso molecular 409.43
Fòrmula C₂₄H₂₁F₂NO₃
Color White to off-white
SMILES

O=C1N(C2=CC=C(F)C=C2)[C@@H](C3=CC=C(O)C=C3)[C@@H]1CC[C@H](C4=CC=C(F)C=C4)O
Synonyms

ent-SCH 58235
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (268 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Lee DH, et al. Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis. Free Radic Biol Med. 2016 Sep 12;99:520-532. [Content Brief]

[2]. Yijun Zhu, et al. Efficient and scalable process for the synthesis of antihypercholesterolemic drug ezetimibe. An International Journal for Rapid Communication of Synthetic Organic Chemistry

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Actividad biológica
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Chemical Information
Pureza y Documentación
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ent-Ezetimibe

Ezetimibe phenoxy glucuronide