HZ52
Based on 1 Customer Validation
HZ52 is a potent, reversible 5-lipoxygenase inhibitor, blocking leukotriene synthesis with an IC50 of 0.7 μM in intact human polymorphonuclear leukocytes.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.3%
- No. CAS: 1077626-51-7
- Fòrmula: C24H26ClN3O2S
- Peso molecular:456.00
-
Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
-
HY-101051
2-TEDC5/12/15-Lipoxygenase Inhibitor -
HY-125975
1-Naphthyl 3,5-dinitrobenzoate5-LOX Inhibitor -
HY-N2075
3-Acetyl-beta-boswellic acidNatural Product -
HY-13750
EbselenVDCC Inhibitor -
HY-119671
BW 755C5-LO/COX Inhibitor -
HY-14164
Zileuton5-Lipoxygenase Inhibitor -
HY-N0892
AKBANrf2 Activator -
HY-N2056
11-Keto-beta-boswellic acidAnti-inflammatory Agent -
HY-103157
PD14617615-LO Inhibitor -
HY-12341
Onvoloxastat12-LOX Inhibitor -
HY-N0892R
AKBA (Standard)Nrf2 Activator -
HY-106200
CJ-13,6105-LO Inhibitor
Actividad biológica
Descripciòn
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
1.6 μM
Compound: 7a
|
Inhibition of PGES1 in human A549 cell microsome assessed as PGE2 formation by cell-free assay
Inhibition of PGES1 in human A549 cell microsome assessed as PGE2 formation by cell-free assay
|
[PMID: 19053751] |
| PMNL | IC50 |
0.7 μM
Compound: 7a
|
Inhibition of 5-LO in PMNL cells
Inhibition of 5-LO in PMNL cells
|
[PMID: 19053751] |
Chemical Information
-
No. CAS 1077626-51-7
-
Appearance Solid
-
Peso molecular 456.00
-
Fòrmula C24H26ClN3O2S
-
Color White to off-white
-
SMILES
ClC1=CC(NC2=CC=C(C=C2)C3=CC=CC=C3)=NC(SC(C(O)=O)CCCCCC)=N1
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
-
Ficha de datos (266 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HZ52 Related Classifications
HY-112553 Related Classifications
Powered by Bioz