JADA3
JADA3 is a molecular glue degrader targeting IKZF1 and IKZF3. JADA3 induces proteasome-mediated degradation of the target transcription factors by binding to the E3 ubiquitin ligase Cereblon. JADA3 can be used in research related to acute myeloid leukemia.
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- No. CAS: 2573901-15-0
- Fòrmula: C10H10ClN3O2
- Peso molecular:239.66
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
[1]|
IKZF1 |
IKZF3 |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Jurkat cells
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Concentration:0.1 and 1 μM
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Incubation Time:24 h
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Result:Induced CRBN-dependent ubiquitination and proteasomal degradation of IKZF1/IKZF3.
Chemical Information
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No. CAS 2573901-15-0
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Peso molecular 239.66
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Fòrmula C10H10ClN3O2
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SMILES
O=CC=1C=NN2C(=O)C(=C(Cl)NC12)C(C)C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JADA3 Related Classifications
HY-W450772 Related Classifications
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