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Referencia número: HY-169634

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JD118

Name: JD118
Brand: MedChemExpress
SKU: HY-169634
Price: 137.00 USD
Availability: InStock
Rating: 5 (1 reviews)

JD118 is a JNK inhibitor. JD118 inhibits JNK1 activity and the expression of cJun (1–135).

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 315704-83-7
Fòrmula: C₁₃H₁₂N₄S₂
Peso molecular:288.39

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

JD118 Chemical Structure

No. CAS: 315704-83-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

JD118 is a JNK inhibitor. JD118 inhibits JNK1 activity and the expression of cJun (1–135)^[1].

Ver todos los productos específicos de isoformas JNK :

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	IC₅₀	44 μM Compound: 7	Antiproliferative activity against MCF7 cells after 72 hrs Antiproliferative activity against MCF7 cells after 72 hrs	[PMID: 17223347]
SK-BR-3	IC₅₀	55 μM Compound: 7	Antiproliferative activity against SkBr3 cells after 72 hrs Antiproliferative activity against SkBr3 cells after 72 hrs	[PMID: 17223347]
SK-BR-3	IC₅₀	61 μM Compound: 7	Induction of Hsp90-dependent Her2 protein degradation in Skbr3 cells after 24 hrs by ELISA Induction of Hsp90-dependent Her2 protein degradation in Skbr3 cells after 24 hrs by ELISA	[PMID: 17223347]

Chemical Information

No. CAS 315704-83-7
Peso molecular 288.39
Fòrmula C₁₃H₁₂N₄S₂
SMILES

CC1=C(SC(N)=N1)C2=CSC(NC3=CC=CC=C3)=N2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Ngoei KR, et al. Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds. Biochim Biophys Acta. 2013;1834(6):1077-1088. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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