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Referencia número: HY-144762

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K027

K027 is a potent reactivator of Organophosphates (OP)-inhibited acetylcholinesterase (AChE). K027 can be used for the research of Alzheimer's disease.

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No. CAS: 6586-37-4
Fòrmula: C₁₅H₁₈Br₂N₄O₂
Peso molecular:446.14

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

K027 Chemical Structure

No. CAS: 6586-37-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Actividad biológica

Descripciòn

K027 is a potent reactivator of Organophosphates (OP)-inhibited acetylcholinesterase (AChE). K027 can be used for the research of Alzheimer's disease^[1].

IC₅₀ & Target

AChE

BChE

Ver todos los productos específicos de isoformas Cholinesterase (ChE) :

AChE
BChE

Chemical Information

No. CAS 6586-37-4
Peso molecular 446.14
Fòrmula C₁₅H₁₈Br₂N₄O₂
SMILES

O=C(C1=CC=[N+](CCC[N+]2=CC=C(C=C2)/C=N/O)C=C1)N.[Br-].[Br-]
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Zuzana Kohoutova, et al. Charged pyridinium oximes with thiocarboxamide moiety are equally or less effective reactivators of organophosphate-inhibited cholinesterases compared to analogous carboxamides. J Enzyme Inhib Med Chem. 2022 Dec;37(1):760-767. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculadora de dilución

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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K027

Ver todos los productos específicos de isoformas Cholinesterase (ChE)

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

K027 Related Classifications

HY-144762 Related Classifications