KIN-8741
KIN-8741 is a highly selective Type IIb c-Met inhibitor. KIN-8741 has broad activity against c-Met kinase mutations. KIN-8741 shows antitumor activity in MET gene amplified and exon 14 deleted non-small cell lung cancer models. KIN-8741 can be used in the research of c-Met driven cancers, especially advanced tumors carrying MET exon 14 jump mutations, acquired drug resistance mutations, etc.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2941104-53-4
- Fòrmula: C26H23F2N3O6
- Peso molecular:511.47
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Chemical Information
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No. CAS 2941104-53-4
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Peso molecular 511.47
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Fòrmula C26H23F2N3O6
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SMILES
FC1=CC(NC(C2=C(C=CN=C2)OC)=O)=CC(F)=C1OC3=CC=NC4=CC(OC)=C(C=C43)O[C@H](CO)C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)