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Referencia número: HY-P5172

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MitTx-alpha

MitTx-alpha is a subunit of MitTx. MitTx is a potent, persistent, and selective agonist for acid-sensing ion channels (ASICs). MitTx is highly selective for the ASIC1 subtype at neutral pH; under more acidic conditions (pH<6.5), MitTx massively potentiates (>100-fold) proton-evoked activation of ASIC2a channels.

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Fòrmula: C₃₁₇H₄₄₀N₈₆O₈₉S₇
Peso molecular:7103.94

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

MitTx-alpha Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

Ver todos los productos específicos de isoformas Sodium Channel :

Chemical Information

Peso molecular 7103.94
Fòrmula C₃₁₇H₄₄₀N₈₆O₈₉S₇
Sequence

{Pyr}-Ile-Arg-Pro-Ala-Phe-Cys-Tyr-Glu-Asp-Pro-Pro-Phe-Phe-Gln-Lys-Cys-Gly-Ala-Phe-Val-Asp-Ser-Tyr-Tyr-Phe-Asn-Arg-Ser-Arg-Ile-Thr-Cys-Val-His-Phe-Phe-Tyr-Gly-Gln-Cys-Asp-Val-Asn-Gln-Asn-His-Phe-Thr-Thr-Met-Ser-Glu-Cys-Asn-Arg-Val-Cys-His-Gly (Disulfide bridge: Cys7-Cys54; Cys17-Cys41; Cys33-Cys58)
Sequence Shortening

{Pyr}-IRPAFCYEDPPFFQKCGAFVDSYYFNRSRITCVHFFYGQCDVNQNHFTTMSECNRVCHG (Disulfide bridge: Cys7-Cys54; Cys17-Cys41; Cys33-Cys58)
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (260 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Christopher J Bohlen, et al. A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain. Nature. 2011 Nov 16;479(7373):410-4. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Actividad biológica
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Chemical Information
Pureza y Documentación
Referencias

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MitTx-alpha

Ver todos los productos específicos de isoformas Sodium Channel