Becotatug vedotin
Based on 1 Customer Validation
Becotatug vedotin (MRG003) is an Antibody-Drug Conjugate (ADC) that consists of an anti-EGFR humanized IgG1 monoclonal antibody Becotatug (HY-P990049) and MMAE (HY-15162). These two parts are connected through a valine-citrulline (valine-citrulline) linker, where the linker and MMAE constitute the ADC's Drug-Linker conjugate VcMMAE (HY-15575). Becotatug vedotin is also an inhibitor of tubulin, which can be used for the research of cancer, such as squamous cell carcinomas of the head and neck, nasopharyngeal carcinoma.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 96.99%
- Peso molecular:149470 (average)
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Almacenamiento:Shipping with dry ice
-80°C, protect from light
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Actividad biológica
Descripciòn
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Liquid
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Peso molecular 149470 (average)
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Color Colorless to light yellow
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SMILES
[Becotatug vedotin]
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Synonyms
MRG003
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Envío
Shipping with dry ice.
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Almacenamiento
-80°C, protect from light
Pureza y Documentación
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Ficha de datos (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Becotatug vedotin
- MRG003
- MRG 003
- MRG-003
- Antibody-Drug Conjugates (ADCs)
- EGFR
- Antibody-Drug Conjugates
- ADC
- Epidermal growth factor receptor
- ErbB-1
- HER1
- monomethyl auristatin E
- nasopharyngeal carcinoma
- squamous cell carcinomas of the head and neck
- valine-citrulline linker
- epidermal growth factor receptor
- humanized immunoglobulin G1 monoclonal antibody
- Inhibitor
- inhibitor
- inhibit