Mycro2
Based on 1 Customer Validation
Mycro2 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC50 value of 23 μM for the inhibition of Myc/Max DNA binding activity. Mycro2 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.81%
- No. CAS: 314049-21-3
- Fòrmula: C17H11F3N4OS2
- Peso molecular:408.42
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Bioactive Compound Library Max
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Bioactive Compound Library
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Cell Proliferation Compound Library
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Lactic Acid Metabolic Compound Library
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High-Throughput Bioactive Compound Library
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Actividad biológica
Mycro2 (10 or 20 μM, 7 days) can inhibit the proliferation of C-Myc-dependent cell lines U-2OS, MCF-7, Raji and NIH/3T3, but does not inhibit the proliferation of C-Myc-independent cancer cell line PC-12. Mycro2 significantly inhibits c-myc-induced gene transcription at 10 μM and selectively reduces unanchored growth of c-myc-transformed Rat1a cells at 20 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 314049-21-3
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Appearance Solid
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Peso molecular 408.42
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Fòrmula C17H11F3N4OS2
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Color Light yellow to yellow
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SMILES
O=C(C1=NN2C(C(F)(F)F)=CC(C3=CC=CS3)=NC2=C1)NCC4=CC=CS4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 125 mg/mL (306.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4485 mL | 12.2423 mL | 24.4846 mL | 61.2115 mL |
| 5 mM | 0.4897 mL | 2.4485 mL | 4.8969 mL | 12.2423 mL | |
| 10 mM | 0.2448 mL | 1.2242 mL | 2.4485 mL | 6.1211 mL | |
| 15 mM | 0.1632 mL | 0.8162 mL | 1.6323 mL | 4.0808 mL | |
| 20 mM | 0.1224 mL | 0.6121 mL | 1.2242 mL | 3.0606 mL | |
| 25 mM | 0.0979 mL | 0.4897 mL | 0.9794 mL | 2.4485 mL | |
| 30 mM | 0.0816 mL | 0.4081 mL | 0.8162 mL | 2.0404 mL | |
| 40 mM | 0.0612 mL | 0.3061 mL | 0.6121 mL | 1.5303 mL | |
| 50 mM | 0.0490 mL | 0.2448 mL | 0.4897 mL | 1.2242 mL | |
| 60 mM | 0.0408 mL | 0.2040 mL | 0.4081 mL | 1.0202 mL | |
| 80 mM | 0.0306 mL | 0.1530 mL | 0.3061 mL | 0.7651 mL | |
| 100 mM | 0.0245 mL | 0.1224 mL | 0.2448 mL | 0.6121 mL |
Mycro2 Related Classifications
HY-126979 Related Classifications
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