NESS 0327
Based on 1 publication(s) in Google Scholar
NESS 0327 is a cannabinoid antagonist with high selectivity for the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.22%
- No. CAS: 494844-07-4
- Fòrmula: C24H23Cl3N4O
- Peso molecular:489.82
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) NESS 0327
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Actividad biológica
Chemical Information
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No. CAS 494844-07-4
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Appearance Solid
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Peso molecular 489.82
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Fòrmula C24H23Cl3N4O
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Color White to off-white
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SMILES
O=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C3=C1CCCC4=CC(Cl)=CC=C43)NN5CCCCC5
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Research (Wash D C)
Endocannabinoids Block Headache and Anxiety Comorbidity via Two-Pronged Anterior Insular Projections. [Abstract]2025 Dec 9:8:1031. PMID: 41377021
Solvente y solubilidad
DMSO : 9.7 mg/mL (19.80 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0416 mL | 10.2078 mL | 20.4157 mL | 51.0392 mL |
| 5 mM | 0.4083 mL | 2.0416 mL | 4.0831 mL | 10.2078 mL | |
| 10 mM | 0.2042 mL | 1.0208 mL | 2.0416 mL | 5.1039 mL | |
| 15 mM | 0.1361 mL | 0.6805 mL | 1.3610 mL | 3.4026 mL |