ONO-7579
ONO-7579 is an orally active TRKA inhibitor that suppresses tumor growth by inhibiting the phosphorylation of TRKA. In colorectal cancer cells KM12, its EC50 is 17.6 ng/g (meaning that when each gram of tumor tissue contains 17.6 ng of ONO-7579, the activity of phosphorylated TRKA in the tumor is inhibited by 50%). ONO-7579 can be used in cancer research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1622212-25-2
- Fòrmula: C24H18ClF3N6O4S
- Peso molecular:578.95
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
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TrkA |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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No. CAS 1622212-25-2
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Peso molecular 578.95
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Fòrmula C24H18ClF3N6O4S
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SMILES
O=C(NC1=CC(C(F)(F)F)=CC=C1S(=O)(C)=O)NC2=CN=C(OC3=CC=C(C4=CC(Cl)=CN=C4N)C=C3)N=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ONO-7579 Related Classifications
HY-164517 Related Classifications
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