PPI stabilizer-1
PPI stabilizer-1-1 (Compound 2) is a KRAS dimerizing agent. PPI stabilizer-1-1 dimerizes KRAS with a KD of 3.8 µM. PPI stabilizer-1-1 co-crystallizes with GCP-KRASG12D. PPI stabilizer-1 can be used for the research of KRAS-driven cancers.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2429876-60-6
- Fòrmula: C40H40N6O4
- Peso molecular:668.78
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
|
KRas G12D |
PPI stabilizer-1 dimerizes KRAS with a KD of 3.8 µM according to isothermal calorimetry measurements[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
No. CAS 2429876-60-6
-
Peso molecular 668.78
-
Fòrmula C40H40N6O4
-
SMILES
O=C(N1)C(C([C@H]1C(C2=CC=CC=C2N3)=C3CNCCCCCCNCC4=C([C@@H]5C6=CC(O)=CC=C6C(N5)=O)C7=CC=CC=C7N4)=C8)=CC=C8O
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PPI stabilizer-1 Related Classifications
HY-185217 Related Classifications
Powered by Bioz