PPZ-A10
Based on 1 Customer Validation
PPZ-A10 is an ionizable cationic lipid. PPZ-A10 preferentially delivers mRNA to liver and spleen immune cells. Pi-LNPs containing PPZ-A10 can effectively deliver mRNA/siRNA to solid tumors.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.90%
- No. CAS: 2941268-67-1
- Fòrmula: C56H114N6O2
- Peso molecular:903.54
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Chemical Information
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No. CAS 2941268-67-1
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Appearance Solid
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Peso molecular 903.54
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Fòrmula C56H114N6O2
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Color Light yellow to yellow
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SMILES
O=C(CCN(CCCCCCCCCC)CCCCCCCCCC)NCCCN1CCN(CCCNC(CCN(CCCCCCCCCC)CCCCCCCCCC)=O)CC1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 100 mg/mL (110.68 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (265 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Ni H, et al. Piperazine-derived lipid nanoparticles deliver mRNA to immune cells in vivo. Nat Commun. 2022;13(1):4766. [Content Brief]
[2]. Subhan MA, et al. Biopolymer-Based Nanosystems for siRNA Drug Delivery to Solid Tumors including Breast Cancer. Pharmaceutics. 2023 Jan 1;15(1):153. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1068 mL | 5.5338 mL | 11.0676 mL | 27.6689 mL |
| 5 mM | 0.2214 mL | 1.1068 mL | 2.2135 mL | 5.5338 mL | |
| 10 mM | 0.1107 mL | 0.5534 mL | 1.1068 mL | 2.7669 mL | |
| 15 mM | 0.0738 mL | 0.3689 mL | 0.7378 mL | 1.8446 mL | |
| 20 mM | 0.0553 mL | 0.2767 mL | 0.5534 mL | 1.3834 mL | |
| 25 mM | 0.0443 mL | 0.2214 mL | 0.4427 mL | 1.1068 mL | |
| 30 mM | 0.0369 mL | 0.1845 mL | 0.3689 mL | 0.9223 mL | |
| 40 mM | 0.0277 mL | 0.1383 mL | 0.2767 mL | 0.6917 mL | |
| 50 mM | 0.0221 mL | 0.1107 mL | 0.2214 mL | 0.5534 mL | |
| 60 mM | 0.0184 mL | 0.0922 mL | 0.1845 mL | 0.4611 mL | |
| 80 mM | 0.0138 mL | 0.0692 mL | 0.1383 mL | 0.3459 mL | |
| 100 mM | 0.0111 mL | 0.0553 mL | 0.1107 mL | 0.2767 mL |
PPZ-A10 Related Classifications
HY-156857 Related Classifications
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