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Referencia número: HY-145454A

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Preclamol

Name: Preclamol
Brand: MedChemExpress
SKU: HY-145454A
Availability: PreOrder

(Synonyms: (-)-3-PPP)

Preclamol is a dopamine (DA) agonist with autoreceptor as well as postsynaptic receptor stimulatory properties. Preclamol inhibits the locomotor activity of mice and rats in low doses.

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No. CAS: 85966-89-8
Fòrmula: C₁₄H₂₁NO
Peso molecular:219.32

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

Preclamol Chemical Structure

No. CAS: 85966-89-8

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Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Preclamol is a dopamine (DA) agonist with autoreceptor as well as postsynaptic receptor stimulatory properties. Preclamol inhibits the locomotor activity of mice and rats in low doses^[1].

Ver todos los productos específicos de isoformas Dopamine Receptor :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	EC₅₀	163 nM Compound: (-)-3PPP	Agonist activity at human D2 receptor expressed in CHO cells by [35S]GTPgammaS binding assay Agonist activity at human D2 receptor expressed in CHO cells by [35S]GTPgammaS binding assay	[PMID: 26555041]
CHO	EC₅₀	376 nM Compound: (-)-3PPP	Antagonist activity against human D2 receptor expressed in CHO cells assessed as dopamine EC50 at 200 nM by [35S]GTPgammaS binding assay (Rvb = 225 +/- 45 nM) Antagonist activity against human D2 receptor expressed in CHO cells assessed as dopamine EC50 at 200 nM by [35S]GTPgammaS binding assay (Rvb = 225 +/- 45 nM)	[PMID: 26555041]
CHO	EC₅₀	51.9 nM Compound: (-)-3PPP	Agonist activity at human D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assay Agonist activity at human D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assay	[PMID: 26555041]
CHO	EC₅₀	844 nM Compound: (-)-3PPP	Antagonist activity against human D2 receptor expressed in CHO cells assessed as dopamine EC50 at 1 uM by [35S]GTPgammaS binding assay (Rvb = 225 +/- 45 nM) Antagonist activity against human D2 receptor expressed in CHO cells assessed as dopamine EC50 at 1 uM by [35S]GTPgammaS binding assay (Rvb = 225 +/- 45 nM)	[PMID: 26555041]

Chemical Information

No. CAS 85966-89-8
Peso molecular 219.32
Fòrmula C₁₄H₂₁NO
SMILES

CCCN1C[C@H](C2=CC(O)=CC=C2)CCC1
Synonyms

(-)-3-PPP
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Preclamol [Content Brief]

[2]. Arnt J, et al. Dopamine receptor agonistic and antagonistic effects of 3-PPP enantiomers. Psychopharmacology (Berl). 1983;81(3):199-207. [Content Brief]

Calculators

Calculadora de molaridad

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Calculadora de dilución

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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