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Referencia número: HY-108009

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Rezafungin

(Synonyms: Biafungin; CD101; SP-3025)

4 Cited Publications

Revisión del cliente

Based on 4 publication(s) in Google Scholar

Rezafungin (Biafungin) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin shows potent antifungal activity against Candida spp., Aspergillus spp., and Pneumocystis spp..

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No. CAS: 1396640-59-7
Fòrmula: C₆₃H₈₅N₈O₁₇
Peso molecular:1226.39

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (279 KB)

Rezafungin Chemical Structure

No. CAS: 1396640-59-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
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- Ensayo clínico
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Publications (4)
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Actividad biológica

Descripciòn

In Vivo

Rezafungin (Biafungin) shows potent in vivo efficacy as prophylaxis against Pneumocystis in a mouse infection model^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

C3H/HeN mice^[1]
Dosage:

1 mg/kg
Administration:

Intraperitoneal injection; once daily for 6 days
Result:

Significantly reduced nuclei and asci burdens.

Ensayo clínico

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

No. CAS 1396640-59-7
Peso molecular 1226.39
Fòrmula C₆₃H₈₅N₈O₁₇
SMILES

O=C1N2[C@]([C@@H](O)[C@@H](C)C2)([H])C(N[C@]([C@@H](C[C@@H](C(N[C@]([C@H](O)C)([H])C(N3[C@](C[C@@H](O)C3)([H])C(N[C@]([C@H](O)[C@H](C4=CC=C(O)C=C4)O)([H])C(N[C@@]1([H])[C@H](O)C)=O)=O)=O)=O)NC(C5=CC=C(C6=CC=C(C7=CC=C(OCCCCC)C=C7)C=C6)C=C5)=O)O)([H])OCC[N+](C)(C)C)=O
Synonyms

Biafungin; CD101; SP-3025
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (4)

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Antimicrob Agents Chemother

Candida parapsilosis and echinocandins: should the clinical laboratory drop anidulafungin Etest from the susceptibility testing panel?. [Abstract]

2025 Aug 6;69(8):e0024125. PMID: 40590712
J Fungi (Basel)

In Vitro Activitiy of Rezafungin in Comparison with Anidulafungin and Caspofungin against Invasive Fungal Isolates (2017 to 2022) in China. [Abstract]

2024 May 31;10(6):397. PMID: 38921383
Microbiol Spectr

Multicenter surveillance of antifungal susceptibility of clinical Aspergillus isolates to conventional and novel antifungal agents in Taiwan, 2021-2023. [Abstract]

2026 Apr 21:e0265925. PMID: 42012212
Preprints

2023 May 17.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (279 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Melanie Cushion, et al. Rezafungin Prophylactic Efficacy in a Mouse Model of Pneumocystis Pneumonia. VOLUME 25, ISSUE 3, SUPPLEMENT, S366, MARCH 01, 2019.

[2]. Sofjan AK, et al. Rezafungin (CD101), a next-generation echinocandin: A systematic literature review and assessment of possible place in therapy. J Glob Antimicrob Resist. 2018 Sep;14:58-64. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Rezafungin

4 Cited Publications

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Rezafungin

Publications Citing Use of MedChemExpress (MCE) Rezafungin

Actividad biológica

Chemical Information

Publications (4)

Pureza y Documentación

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Rezafungin Related Classifications

HY-108009 Related Classifications