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Referencia número: HY-N10204

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Rostratin B

Rostratin B, a cytotoxic disulfide, shows in vitro cytotoxicity against human colon carcinoma (HCT-116) with IC₅₀ of 1.9 μg/mL.

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No. CAS: 752236-17-2
Fòrmula: C₁₈H₂₀N₂O₆S₂
Peso molecular:424.49

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Rostratin B Chemical Structure

No. CAS: 752236-17-2

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- Cellular Effect
Chemical Information
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Actividad biológica

Descripciòn

Rostratin B, a cytotoxic disulfide, shows in vitro cytotoxicity against human colon carcinoma (HCT-116) with IC₅₀ of 1.9 μg/mL^[1].

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Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	4.4 μM Compound: 2	Cytotoxicity against human HCT116 cells Cytotoxicity against human HCT116 cells	[PMID: 15332857]

Chemical Information

No. CAS 752236-17-2
Peso molecular 424.49
Fòrmula C₁₈H₂₀N₂O₆S₂
SMILES

O=C(N1[C@]([C@H](CC2)O)([H])[C@](C2=O)([H])C3)[C@@]4(SS[C@]13C5=O)N5[C@]([C@H](CC6)O)([H])[C@](C6=O)([H])C4
Structure Classification
- Alkaloids
- Pyrrole Alkaloids
Initial Source
- Microorganisms
Exserohilum rostratum
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

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Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Tan RX, et al. Isolation and structure assignments of rostratins A-D, cytotoxic disulfides produced by the marine-derived fungus Exserohilum rostratum. J Nat Prod. 2004;67(8):1374-1382. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Rostratin B

Ver todos los productos específicos de isoformas Endogenous Metabolite

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

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Rostratin B Related Classifications

HY-N10204 Related Classifications