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United States

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Referencia número: HY-183782

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SA1103064

SA1103064 is a potent antibiotic with antibacterial activity against multiple resistant bacterial strains. SA1103064 binds to the bacterial ribosome's nascent peptide exit tunnel. SA1103064 can be used for the research of bacterial infections.

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Fòrmula: C₃₉H₅₀FN₇O₆
Peso molecular:731.86

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

SA1103064 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

Ver todos los productos específicos de isoformas Antibiotic :

In Vitro

SA1103064 (compound 48a) binds to the E. coli ribosome's nascent peptide exit tunnel, forming π-stacking interactions with U1782-U2586 and van der Waals interactions with U2585, occupying the site of tetracenomycin X and mimicking VS1 binding contacts^[1].
SA1103064 exhibits potent antibacterial activity against multiple Gram-positive strains, including drug-resistant isolates, with MIC values ranging from 1 to 8 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

Peso molecular 731.86
Fòrmula C₃₉H₅₀FN₇O₆
SMILES

[H][C@]12CCCN1C(C3=COC(C[C@@H](C[C@@H](/C=C(/C=C/CNC(/C=C/[C@H]([C@H](OC2=O)C(C)C)CCCCCN4C=C(N=N4)C5=CC=NC=C5)=O)C)O)F)=N3)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Lee IJ, et al. Structure-based design and synthesis of group A streptogramins that bind to the nascent peptide exit tunnel of the ribosome. Eur J Med Chem. 2026 May 9;316:118947. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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