Salinomycin (Standard)
Salinomycin (Standard) is the analytical standard of Salinomycin. This product is intended for research and analytical applications. Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, selectively inhibits the growth of gram-positive bacteria. Salinomycin is a potent inhibitor of Wnt/β-catenin signaling, blocks Wnt-induced LRP6 phosphorylation. Salinomycin shows selective activity against human cancer stem cells[1][2][3].
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 95%
- No. CAS: 53003-10-4
- Fòrmula: C42H70O11
- Peso molecular:751.00
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureza y Documentación
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Help & FAQs
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HY-15597
SalinomycinPotassium Ionophore Antibiotic -
HY-13912
IWP-2Wnt Production Inhibitor -
HY-17439
Salinomycin sodium saltWnt/β-catenin Inhibitor -
HY-12238
IWR-1Wnt Signaling Inhibitor -
HY-14428
ICG-001Apoptosis Inducer -
HY-16268
KartogeninChondroprotective Agent -
HY-120697
MSABWnt/β-Catenin Inhibitor -
HY-15659
Wnt-C59PORCN Inhibitor -
HY-12323
ISX-9Neural Stem Cell Differentiation Inducer -
HY-17545
LGK974PORCN Inhibitor -
HY-15721
FH535Wnt/β-catenin/PPAR Inhibitor -
HY-101130
PNU-74654β-catenin/TCF Interaction Inhibitor
Product Information
Information
Aplicación
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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No. CAS 53003-10-4
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Peso molecular 751.00
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Fòrmula C42H70O11
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SMILES
[H][C@]1([C@](C)(CC2)O[C@]32[C@H](O)C=C[C@]4(O[C@]([H])([C@@H](CC)C([C@@H](C)[C@@H](O)[C@H](C)[C@]5([H])O[C@]([C@@H](CC)C(O)=O)([H])CC[C@@H]5C)=O)[C@@H](C)C[C@H]4C)O3)CC[C@@](CC)(O)[C@H](C)O1
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Synonyms
Procoxacin (Standard)
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Lu D, et al. Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13253-7. [Content Brief]
[2]. Zhou J, et al. Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactiveoxygen species. Toxicol Lett. 2013 Oct 24;222(2):139-45. [Content Brief]
[3]. Klose J, et al. Salinomycin: Anti-tumor activity in a pre-clinical colorectal cancer model. PLoS One. 2019 Feb 14;14(2):e0211916. [Content Brief]
[4]. Wang F, et al. Salinomycin Inhibits Proliferation and Induces Apoptosis of Human Hepatocellular Carcinoma Cells In Vitro and In Vivo. PLoS One. 2012; 7(12): e50638. [Content Brief]
[5]. Qu H, et al. Effect of salinomycin on metastasis and invasion of bladder cancer cell line T24. Asian Pac J Trop Med. 2015 Jul;8(7):578-82. [Content Brief]
[6]. Naujokat C, et al. Salinomycin as a drug for targeting human cancer stem cells. J Biomed Biotechnol. 2012;2012:950658. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Salinomycin (Standard) Related Classifications
HY-15597R Related Classifications
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