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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2438 Results for "
decrease
" in MedChemExpress (MCE) Product Catalog:
Products (2438)
2438 Results for "decrease" in MCE Product Catalog:
Referencia número: HY-B0094S
No. CAS: 176652-07-6
Synonyms: Qinghaosu-d3; NSC 369397-d3
Referencia número: HY-B0523B
No. CAS: 823178-43-4
Target:
Áreas de investigación:
Anagrelide hydrochloride monohydrate is a potent inhibitor of phosphodiesterase type III (PDE3) (IC50=36 nM). Anagrelide hydrochloride monohydrate, an imidazoquinazoline derivative, acts as an inhibitor of platelet aggregation. Anagrelide hydrochloride monohydrate inhibits bone marrow megakaryocytopoiesis. Anagrelide hydrochloride monohydrate decreases gastrointestinal stromal tumor (GIST) cell proliferation and promotes their apoptosis in vitro. Anagrelide hydrochloride monohydrate is a platelet-lowering agent and plays in the antithrombopoietic action .
Referencia número: HY-B0588R
No. CAS: 138890-62-7
Synonyms: AL-4862 (Standard)
Áreas de investigación:
Brinzolamide (Standard) is the analytical standard of Brinzolamide. This product is intended for research and analytical applications. Brinzolamide (AL-4862) is a selective carbonic anhydrase II inhibitor with anIC50 value of 3.2 nM. Brinzolamide hydrochloride reduces intraocular pressure (IOP) by inhibiting ciliary CA-II and decreasing atrial fluid secretion. Brinzolamide can be used in glaucoma disease research .
Referencia número: HY-B2099S
Synonyms: 1-Butylbiguanide-d9 hydrochloride
Referencia número: HY-N0158R
No. CAS: 16837-52-8
Referencia número: HY-N11772R
No. CAS: 875455-92-8
Category:
Target:
Referencia número: HY-N12042
No. CAS: 110300-77-1
Referencia número: HY-N19627
No. CAS: 607357-35-7
Synonyms: 3′-M-ECG
Category:
Plant Flavonoids Camellia sinensis (L.) O. Ktze. Extract Other Flavonoids Theaceae Extract
Target:
Referencia número: HY-N5097
No. CAS: 29623-29-8
Target:
Target:
Áreas de investigación:
Referencia número: HY-P11782
No. CAS: 254732-11-1
Referencia número: HY-P1306
No. CAS: 869705-22-6
Target:
Áreas de investigación:
Referencia número: HY-P99608
No. CAS: 569658-80-6
Referencia número: HY-W017448
No. CAS: 24307-26-4
Synonyms: N,N-Dimethylpiperidinium chloride; PIX
Áreas de investigación:
Mepiquat chloride (N,N-Dimethylpiperidinium chloride) is a systemic plant growth regulator. Mepiquat chloride reduces the activity of RuBP carboxylase. Mepiquat chloride decreases plant height, total length of vegetative and fruiting branches, and total leaf area of cotton. Mepiquat chloride reduces the net photosynthetic rate of cotton leaves. Mepiquat chloride promotes starch accumulation in cotton leaves without altering sucrose content .
Referencia número: HY-W110242A
No. CAS: 194979-70-9
Target:
Áreas de investigación:
(S)-CPP sodium serves as an inhibitor of the branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, commonly referred to as BDK or keto acid dehydrogenase kinase. As a negative regulator of BCKDC activity, the inhibition of BDK by (S)-CPP (with an IC50 of 6.3 μM) results in the activation of the complex and a notable decrease in plasma levels of leucine/isoleucine and valine in wild-type mice.
Referencia número: HY-W201317
No. CAS: 1060968-92-4
Target:
Áreas de investigación:
E17241 is an inducer of the expression of ABCA1 that increases the protein levels of ABCA1 in RAW 264.7 macrophages. E17241 is also an agonist of peroxisome proliferator-activated receptors (PPARs ). E17241 decreases plasma glucose levels and body weight in KKAy diabetic mice fed a high-fat and high-glucose (HFHG) diet .
Referencia número: HY-W707564
Referencia número: HY-112726A
No. CAS: 1478364-40-7
Synonyms: BI-1467335 free base
Áreas de investigación:
PXS-4728A free base is an orally active, selective VAP-1/SSAO inhibitor with an IC50 of 5 nM and a Ki of 175 nM. PXS-4728A free base inhibits the expression of MMP-9. It reduces cell rolling, adhesion and migration, decreases cell infiltration levels, pro-inflammatory cytokines, chemokines and collagen deposition, and improves pulmonary function. PXS-4728A free base reduces the formation and progression of atherosclerotic plaques, and decreases blood lipid and blood glucose levels as well as body weight gain. PXS-4728A free base can be used in research related to chronic obstructive pulmonary disease, cystic fibrosis, acute pulmonary inflammation, acute lung injury, bronchiolitis obliterans syndrome, rhinovirus-exacerbated asthma, sepsis, Klebsiella pneumoniae pulmonary infection and atherosclerosis .
Referencia número: HY-169480
No. CAS: 3003022-09-8
Lipid C2 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNP) for mRNA delivery in vivo. LNPs containing Lipid C2 and encapsulating an mRNA reporter selectively accumulate in the liver and spleen but not the heart, lungs, or kidneys in mice. LNP containing Lipid C2 and encapsulating mRNA encoding the Epstein-Barr virus (EBV) protein latent membrane protein 2 (LMP-2), in combination with an anti-programmed cell death protein 1 (PD-1) antibody, decrease tumor volume and reverse T cell exhaustion, as well as increase the percentage of CD3 +CD8 + central and CD3 +CD8 + effector memory T cells and decrease the percentage of CD3 + T cells expressing Pd-1, in the spleen in a CT26 murine EBV-infected colon cancer model .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
