SM27
SM27 (NSC 37204) is an inhibitor for fibroblast growth factors (FGF). SM27 inhibits angiogenesis through block of FGF2/HSPGs/FGFR1 complex formation.
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- No. CAS: 6266-54-2
- Fòrmula: C21H16N2O9S2
- Peso molecular:504.49
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
In Vitro
SM27 (0-100 μM, 2 h) inhibits FGF2/heparin and FGF2/ FGFR1 interaction in a dose-dependent way with IC50s of 3.5 and 4 mM, through inhibition of FGF2-mediated cell-cell adhesion with IC50 of 1 mM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 6266-54-2
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Peso molecular 504.49
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Fòrmula C21H16N2O9S2
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SMILES
O=S(C1=CC(O)=C2C=C(C=CC2=C1)NC(NC3=CC=C4C=C(C=C(C4=C3)O)S(=O)(O)=O)=O)(O)=O
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Synonyms
NSC 37204
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SM27 Related Classifications
HY-123453 Related Classifications
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