SNAP 398299
SNAP 398299 is a Gal3 receptor antagonist with potential anxiolytic and antidepressant effects. SNAP 398299 can partially reverse the neuropeptide Galanin-induced inhibition of dorsal raphe cell firing and the Galanin-induced hyperpolarizing current.
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- No. CAS: 903878-06-8
- Fòrmula: C27H24F3N3O2
- Peso molecular:479.49
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
Chemical Information
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No. CAS 903878-06-8
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Peso molecular 479.49
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Fòrmula C27H24F3N3O2
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SMILES
O=C1/C(C2=CC=CC=C2N1C3=CC(OCCN4CCCC4)=CC=C3)=N/C5=CC=CC(C(F)(F)F)=C5
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Swanson CJ, et al. Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17489-94. [Content Brief]
[2]. Insights of structure-based pharmacophore studies and inhibitor design against Gal3 receptor through molecular dynamics simulations [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SNAP 398299 Related Classifications
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