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Referencia número: HY-159888

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SON38

SON38 is a copper chelator capable of chelating divalent copper. SON38 can inhibit the activity of cholinesterases and has potential applications in Alzheimer's disease research.

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No. CAS: 3034673-37-2
Fòrmula: C₂₁H₂₅ClN₄O₄
Peso molecular:432.90

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

SON38 Chemical Structure

No. CAS: 3034673-37-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

SON38 is a copper chelator capable of chelating divalent copper. SON38 can inhibit the activity of cholinesterases and has potential applications in Alzheimer's disease research^[1].

Ver todos los productos específicos de isoformas Cholinesterase (ChE) :

AChE
BChE

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	>100 μM Compound: 12; SON38	Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay	[PMID: 35462163]
HepG2	IC₅₀	>100 μM Compound: 12; SON38	Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay	[PMID: 35462163]
SH-SY5Y	IC₅₀	>100 μM Compound: 12; SON38	Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay	[PMID: 35462163]
SH-SY5Y	IC₅₀	>100 μM Compound: 12; SON38	Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay	[PMID: 35462163]

Chemical Information

No. CAS 3034673-37-2
Peso molecular 432.90
Fòrmula C₂₁H₂₅ClN₄O₄
SMILES

ClC1=CC([N+]([O-])=O)=C(C=C1)OCC(NCCN2CCN(CC2)CC3=CC=CC=C3)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Leuci R, et al. Rivastigmine structure-based hybrids as potential multi-target anti-Alzheimer’s drug candidates[J]. Bioorganic Chemistry, 2024, 153: 107895. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Actividad biológica
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Chemical Information
Pureza y Documentación
Referencias

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SON38

Ver todos los productos específicos de isoformas Cholinesterase (ChE)

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

SON38 Related Classifications

HY-159888 Related Classifications