Taltrimide
Taltrimide (MY-117), a lipophilic derivative of Taurine (HY-B0351), strongly inhibits the sodium-independent binding of Taurine to synaptic membranes of brain, the effects on the binding of GABA being less pronounced. Taltrimide exhibits definitive anticonvulsive effects in experimental epilepsy models.
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- No. CAS: 81428-04-8
- Fòrmula: C13H16N2O4S
- Peso molecular:296.34
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
Chemical Information
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No. CAS 81428-04-8
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Appearance Solid
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Peso molecular 296.34
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Fòrmula C13H16N2O4S
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Color Light yellow to yellow
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SMILES
O=S(CCN(C(C1=C2C=CC=C1)=O)C2=O)(NC(C)C)=O
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Synonyms
MY-117
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (269 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Airaksinen EM, et, al. Biochemical and clinical studies on epileptic patients during two phase I trials with the novel anticonvulsant taltrimide. Epilepsy Res. 1987 Sep;1(5):308-11. [Content Brief]
[2]. Keränen T, et, al. Effects of taltrimide, an experimental taurine derivative, on photoconvulsive response in epileptic patients. Epilepsia. 1987 Mar-Apr;28(2):133-7. [Content Brief]
[3]. Kontro P, et, al. Effects of the anticonvulsant taurine derivative, taltrimide, on membrane transport and binding of GABA and taurine in the mouse cerebrum. Neuropharmacology. 1987 Jan;26(1):19-23. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Taltrimide Related Classifications
HY-106469 Related Classifications
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