TD114-2
TD114-2 (cmpound 29) is a potent and highly selective inhibitor of glycogen synthase kinase-3β (GSK-3β) (IC50=48 nM). TD114-2 is associated with the hydrogen bond formation of arginine 141 (ARG141) specific to GSK-3β, an amino acid that is often a negatively charged residue in other kinases, which determines the high selectivity of GSK-3β. TD114-2 can be used in the study of diabetes, neurodegenerative diseases and other diseases associated with GSK-3β.
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- No. CAS: 436866-52-3
- Fòrmula: C30H31N3O6
- Peso molecular:529.58
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 436866-52-3
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Peso molecular 529.58
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Fòrmula C30H31N3O6
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SMILES
O=C(N1)C(C2=CN(CCOCCOCCOCCOCC3)C4=CC=CC=C24)=C(C1=O)C5=CN3C6=CC=CC=C56
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TD114-2 Related Classifications
HY-136679 Related Classifications
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