Copy Link Print Information

Trontinemab

(Synonyms: RG6102; RO-7126209)
Revisión del cliente

Based on 1 Customer Validation

Trontinemab (RG6102) is a brain-penetrant, anti-amyloid, bispecific and humanizedized IgG1-κ antibody, targeting to Aβ plaques and transferrin receptor 1 (TFR1). Trontinemab binds to fibrillar Aβ as well as Aβ plaques triggering plaque clearance by engaging immune cells on Alzheimer disease (AD) brain sections. Trontinemab also shows specific affinity to cynomolgus and human TFR1.

Para uso exclusivo en investigación. No vendemos a pacientes.

  • Pureza: 99.93%
  • No. CAS: 2568868-35-7
  • Peso molecular:194.25 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Trontinemab
  • Experimental Validation Results for Trontinemab
  • Experimental Validation Results for Trontinemab
  • Experimental Validation Results for Trontinemab
  • Trontinemab Chemical Structure
    Trontinemab Chemical Structure
No. CAS: 2568868-35-7
Tamaño
Precio
Stock
Cantidad
Amount: USD 0.00
Please select quantity
or
or

* Seleccione Cantidad antes de agregar artículos.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Trontinemab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
  • Actividad biológica
  • Chemical Information
  • Pureza y Documentación
  • Referencias
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products
Keywords
MOQ
Minimum order quantity
100 mg

Obtener un presupuesto En stock

Other size
Obtener un presupuesto
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Inicie sesiòn
Registrar
Sign in to MedChemExpress
Registrar una cuenta nueva

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    IgG1-kappa-(Fab G1-kappa with domain crossover)

  • 1/16

    IgG1-kappa-(Fab G1-kappa with domain crossover)

  • 1/16

    Immobilized Human Beta-amyloid/Beta-APP Protein (hFc Tag) can bind Trontinemab. The EC50 for this effect is 34.64 ng/mL.

  • 1/16

    Immobilized HY-P71069 TFRC Protein, Human (HEK293, His) can bind Trontinemab. The EC50 for this effect is 193.5 ng/mL.

  • Trontinemab Chemical Structure
    1/16
  • Trontinemab
  • Immobilized Human Beta-amyloid/Beta-APP Protein (hFc Tag) can bind Trontinemab. The EC50 for this effect is 34.64 ng/mL.
  • Immobilized HY-P71069 TFRC Protein, Human (HEK293, His) can bind Trontinemab. The EC50 for this effect is 193.5 ng/mL.
  • IgG1-kappa-(Fab G1-kappa with domain crossover)
  • IgG1-kappa-(Fab G1-kappa with domain crossover)