Valilactone
Based on 1 Customer Validation
Valilactone is a potent and effective inhibitor of esterase, produced by actinomycetes.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.2%
- No. CAS: 113276-96-3
- Fòrmula: C22H39NO5
- Peso molecular:397.55
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
Descripciòn
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-435 | IC50 |
10.5 μM
Compound: valilactone
|
Cytotoxicity against human MDA-MB-435 cells after 48 hrs by Cell titer assay
Cytotoxicity against human MDA-MB-435 cells after 48 hrs by Cell titer assay
|
[PMID: 18710210] |
Chemical Information
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No. CAS 113276-96-3
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Appearance Solid
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Peso molecular 397.55
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Fòrmula C22H39NO5
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Color White to off-white
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SMILES
CCCCCC[C@H]1[C@@H](OC1=O)C[C@H](CCCCC)OC([C@H](C(C)C)NC=O)=O
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Synonyms
(-)-Valilactone
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Structure Classification
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Initial Source
actinomycetes
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 25 mg/mL (62.89 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5154 mL | 12.5770 mL | 25.1541 mL | 62.8852 mL |
| 5 mM | 0.5031 mL | 2.5154 mL | 5.0308 mL | 12.5770 mL | |
| 10 mM | 0.2515 mL | 1.2577 mL | 2.5154 mL | 6.2885 mL | |
| 15 mM | 0.1677 mL | 0.8385 mL | 1.6769 mL | 4.1923 mL | |
| 20 mM | 0.1258 mL | 0.6289 mL | 1.2577 mL | 3.1443 mL | |
| 25 mM | 0.1006 mL | 0.5031 mL | 1.0062 mL | 2.5154 mL | |
| 30 mM | 0.0838 mL | 0.4192 mL | 0.8385 mL | 2.0962 mL | |
| 40 mM | 0.0629 mL | 0.3144 mL | 0.6289 mL | 1.5721 mL | |
| 50 mM | 0.0503 mL | 0.2515 mL | 0.5031 mL | 1.2577 mL | |
| 60 mM | 0.0419 mL | 0.2096 mL | 0.4192 mL | 1.0481 mL |