TOMM6 - translocase of outer mitochondrial membrane 6 Gene

Also Known as OBTP; TOM6

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 100188893

About TOMM6

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:41,787,694-41,789,895 (from NCBI)

This gene has 2 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in adrenal (RPKM 63.4), kidney (RPKM 57.9) and 25 other tissues.

Summary

Predicted to be involved in protein transport. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

TOMM6 Products (2)

mRNA Protein Name
NM_001134493.2 NP_001127965.1 mitochondrial import receptor subunit TOM6 homolog
NM_001382294.1 NP_001369223.1 mitochondrial import receptor subunit TOM6 homolog

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TOMM6 Protein Structure

TOM6p

TOM6p: Mitochondrial import receptor subunit TOM6 homolog (1 - 74)

  • 0
  • 74 a.a.
Protein Preferred Names Protein Names

mitochondrial import receptor subunit TOM6 homolog

  • over-expressed breast tumor protein

TOMM6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TOMM6 Q96B49 ODF4 Homo sapiens Q2M2E3
Y2H Array
32296183
Intra
TOMM6 Q96B49 ODF4 Homo sapiens Q2M2E3
Y2H Prey Pooling
32296183
Intra
TOMM6 Q96B49 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra
TOMM6 Q96B49 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra
TOMM6 Q96B49 C1orf159 Homo sapiens Q96HA4-2
Y2H Array
32296183
Intra
TOMM6 Q96B49 C1orf159 Homo sapiens Q96HA4-2
Y2H Prey Pooling
32296183
Intra
TOMM6 Q96B49 C1orf159 Homo sapiens Q96HA4-2
Validated Y2H
32296183
Intra
TOMM6 Q96B49 FFAR3 Homo sapiens O14843
Y2H Prey Pooling
32296183
Intra
TOMM6 Q96B49 FFAR3 Homo sapiens O14843
Y2H Array
32296183
Intra
TOMM6 Q96B49 SLC18A2 Homo sapiens Q05940
Y2H Array
32296183
Intra
TOMM6 Q96B49 SLC18A2 Homo sapiens Q05940
Y2H Prey Pooling
32296183
Intra
TOMM6 Q96B49 CERS4 Homo sapiens Q9HA82
Validated Y2H
32296183
Intra
TOMM6 Q96B49 CERS4 Homo sapiens Q9HA82
Y2H Array
32296183
Intra
TOMM6 Q96B49 CERS4 Homo sapiens Q9HA82
Y2H Prey Pooling
32296183
Intra
TOMM6 Q96B49 CD68 Homo sapiens P34810
Y2H Prey Pooling
32296183
Intra
TOMM6 Q96B49 CD68 Homo sapiens P34810
Y2H Array
32296183
Intra
TOMM6 Q96B49 SLC10A1 Homo sapiens Q14973
Y2H Array
32296183
Intra
TOMM6 Q96B49 SLC10A1 Homo sapiens Q14973
Y2H Prey Pooling
32296183
Intra
TOMM6 Q96B49 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
Intra
TOMM6 Q96B49 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
Intra
TOMM6 Q96B49 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
Intra
TOMM6 Q96B49 TMEM14B Homo sapiens Q9NUH8
Validated Y2H
32296183
Intra
TOMM6 Q96B49 TMEM14B Homo sapiens Q9NUH8
Y2H Array
32296183
Intra
TOMM6 Q96B49 TMEM14B Homo sapiens Q9NUH8
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-183057 GRK2 modulator 1 / Unkown
HY-RS14885 TOMM6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TOMM6 RGD RGD:1583567
Canis familiaris TOMM6 VGNC VGNC:49103
Felis catus TOMM6 VGNC VGNC:102539
Mus musculus TOMM6 MGD MGI:1913369
Others TOMM6 NCBI