EMB - embigin Gene

Also Known as GP70

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 133418

About EMB

Cytogenetic location: 5q11.1 Genomic coordinates (GRCh38): 5:50,396,192-50,443,345 (from NCBI)

This gene has 5 transcripts (splice variants), 192 orthologues and 3 paralogues. Broad expression in bone marrow (RPKM 76.3), duodenum (RPKM 39.2) and 16 other tissues.

Summary

This gene encodes a Transmembrane Glycoprotein that is a member of the immunoglobulin superfamily. The encoded protein may be involved in cell growth and development by mediating interactions between the cell and extracellular matrix. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Jan 2009]

EMB Products (1)

mRNA Protein Name
NM_198449.3 NP_940851.1 embigin precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
33961781 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EMB Protein Structure

Ig_2

Ig_2: Immunoglobulin domain (76 - 146)

I-set

I-set: Immunoglobulin I-set domain (161 - 254)

  • 0
  • 100
  • 200
  • 300
  • 327 a.a.
Protein Preferred Names Protein Names

embigin

  • embigin homolog

EMB Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
EMB Q6PCB8 BCS1L Homo sapiens Q9Y276
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Splenic Manifestation Of Leukemia

  • Splenic Leukemia
Sporotrichosis

  • Rose Gardener'S Disease
Primary Systemic Mycosis
Conidiobolomycosis

  • Infection By Conidiobolus

  • Rhinoentomophthoromycosis

  • Entomophthoromycosis Conidiobolae
Subcutaneous Mycosis

  • Subcutaneous Fungal Disease
Null-Cell Leukemia

  • Null Cell Acute Lymphoblastic Leukemia

  • Null Cell Acute Lymphoblastic Leukaemia

  • Null-Cell Leukaemia
Acute Erythroid Leukemia

  • Acute Erythroleukemia

  • Di Guglielmo'S Syndrome

  • Aml M6

  • Acute Myeloid Leukemia Fab-M6

  • Acute Myeloid Leukemia M6

  • Erythroleukemia

  • Aml-M6

  • Acute Erythroleukemia M6a Subtype

  • Acute Erythroleukemia M6b Subtype

  • Di Guglielmo Syndrome

  • Acute Myeloid Leukemia, M6 Type

  • Acute Erythroblastic Leukemia

  • Acute Erythroleukemia - M6a Subtype

  • Acute Erythroleukemia - M6b Subtype

  • Acute Erythraemia And Erythroleukaemia

  • Acute Erythroid Leukaemia Without Mention Of Remission

  • Erythraemia

  • Erythraemic Myelosis

  • Erythroleukaemia

  • Acute Erythraemic Myelosis

  • Acute Erythraemia
Developmental And Epileptic Encephalopathy 24

  • DEE24

  • Epileptic Encephalopathy, Early Infantile, 24

  • Eiee24

  • Developmental And Epileptic Encephalopathy, 24

  • Early Infantile Epileptic Encephalopathy 24

  • Encephalopathy, Epileptic, Early Infantile, Type 24
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0535A Ethambutol dihydrochloride Inhibitor 99.91% Yes
HY-B0535AR Ethambutol dihydrochloride (Standard) Inhibitor 99.87% Unkown

Clinical Phase

Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99455 Bafisontamab Inhibitor 99.9% Phase 3
HY-P990740 Fanastomig 95.478% Phase 2

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-B0535S Ethambutol-d4 Inhibitor 98.12% Unkown
HY-RS15889 XPO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-157352 Eosin-Methylene Blue Agar / Unkown
HY-157364 Levine Eosin-Methylene Blue Agar Medium / Unkown
HY-B0535AS Ethambutol-d4 dihydrochloride Inhibitor / Unkown
HY-B0535S1 Ethambutol-d10 Inhibitor 99.0% Unkown
HY-B0535S2 Ethambutol-d8 Inhibitor / Unkown
HY-RS04334 EMB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16761 Emb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23200 Emb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990980 Cizutamig Inhibitor 95% Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus EMB RGD RGD:621067
Mus musculus EMB MGD MGI:95321
Canis familiaris EMB VGNC VGNC:50876
Felis catus EMB VGNC VGNC:102194
Macaca mulatta EMB VGNC VGNC:72144
Others EMB NCBI