EMB - embigin Gene

Homo sapiens

Also known as GP70

Gene ID: 133418 | Gene type: protein coding

About EMB

Cytogenetic location: 5q11.1 Genomic coordinates (GRCh38): 5:50,396,192-50,443,345 (from NCBI)

This gene has 5 transcripts (splice variants), 192 orthologues and 3 paralogues. Broad expression in bone marrow (RPKM 76.3), duodenum (RPKM 39.2) and 16 other tissues.

Summary

This gene encodes a transmembrane glycoprotein that is a member of the immunoglobulin superfamily. The encoded protein may be involved in cell growth and development by mediating interactions between the cell and extracellular matrix. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Jan 2009]

EMB Products(1)

mRNA	Protein	Name
NM_198449.3	NP_940851.1	embigin precursor

EMB Protein Structure

Ig_2

I-set

0
100
200
300
327 a.a.

Protein Preferred Names

Protein Names

embigin

embigin homolog

Recombinant EMB Proteins

Cat. No.	Product Name	Accession	Purity
HY-P79054	Embigin/EMB Protein, Human (HEK293, hFc)	Q6PCB8 (D33-P260)	≥95%

Related Diseases

Diseases

Alias

Splenic Manifestation Of Leukemia

Splenic Leukemia

Sporotrichosis

Rose Gardener'S Disease

Primary Systemic Mycosis

Conidiobolomycosis

Infection By Conidiobolus	Rhinoentomophthoromycosis
Entomophthoromycosis Conidiobolae

Subcutaneous Mycosis

Subcutaneous Fungal Disease

Null-Cell Leukemia

Null Cell Acute Lymphoblastic Leukemia	Null Cell Acute Lymphoblastic Leukaemia
Null-Cell Leukaemia

Acute Erythroid Leukemia

Acute Erythroleukemia	Di Guglielmo'S Syndrome
Aml M6	Acute Myeloid Leukemia Fab-M6
Acute Myeloid Leukemia M6	Erythroleukemia
Aml-M6	Acute Erythroleukemia M6a Subtype
Acute Erythroleukemia M6b Subtype	Di Guglielmo Syndrome
Acute Myeloid Leukemia, M6 Type	Acute Erythroblastic Leukemia
Acute Erythroleukemia - M6a Subtype	Acute Erythroleukemia - M6b Subtype
Acute Erythraemia And Erythroleukaemia	Acute Erythroid Leukaemia Without Mention Of Remission
Erythraemia	Erythraemic Myelosis
Erythroleukaemia	Acute Erythraemic Myelosis
Acute Erythraemia

Developmental And Epileptic Encephalopathy 24

DEE24	Epileptic Encephalopathy, Early Infantile, 24
Eiee24	Developmental And Epileptic Encephalopathy, 24
Early Infantile Epileptic Encephalopathy 24	Encephalopathy, Epileptic, Early Infantile, Type 24

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-B0535A	Ethambutol dihydrochloride	Inhibitor	98.75%	Yes
HY-B0535	Ethambutol	Inhibitor	/	Unkown
HY-B0535AR	Ethambutol dihydrochloride (Standard)	Inhibitor	/	Unkown

Clinical Phase

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99455	Bafisontamab	Inhibitor	96.00%	Phase 3

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-B0535S	Ethambutol-d4	Inhibitor	98.12%	Unkown
HY-B0535S1	Ethambutol-d10	Inhibitor	≥99.0%	Unkown
HY-B0535S2	Ethambutol-d8	Inhibitor	/	Unkown
HY-RS04334	EMB Human Pre-designed siRNA Set A		/	Unkown
HY-B0535AS	Ethambutol-d4 dihydrochloride	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	EMB	RGD	RGD:621067
Mus musculus	EMB	MGD	MGI:95321
Canis familiaris	EMB	VGNC	VGNC:50876
Felis catus	EMB	VGNC	VGNC:102194
Macaca mulatta	EMB	VGNC	VGNC:72144
Macaca fascicularis	EMB	NCBI
Leporidae	EMB	NCBI
Others	EMB	NCBI

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