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Bafisontamab

(Synonyms: EMB-01)
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Bafisontamab (EMB-01) is a bispecific antibody targeting EGFR and cMET with antitumor activity.

For research use only. We do not sell to patients.

  • Purity: 99.9%
  • CAS No.: 2437210-79-0
  • Molecular Weight:237.63 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Bafisontamab
  • Experimental Validation Results for Bafisontamab
  • Experimental Validation Results for Bafisontamab
  • Experimental Validation Results for Bafisontamab
  • Experimental Validation Results for Bafisontamab
  • Bafisontamab Chemical Structure
    Bafisontamab Chemical Structure
CAS No.: 2437210-79-0
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609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    [(G1 VK-CK-VH-CH1-h-CH2-CH3_L-kappa)_VH-CH1]-dimer

  • 1/16

    Immobilized Bafisontamab can bind Human EGFR Protein (ECD, His Tag). The EC50for this effect is 3.76 ng/mL.

  • 1/16

    Immobilized Bafisontamab can bind Human c-MET/HGFR Protein (ECD, His Tag). The EC50 for this effect is 3.28 ng/mL.

  • 1/16

    Flow Cytometry analysis of Hela cells labelling EGFR (red) with Bafisontamab (HY-P99455). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Flow cytometric analysis of 1X106 HT-29 cells labeling MET with Bafisontamab (HY-P99455, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Bafisontamab Chemical Structure
    1/16
  • Bafisontamab
  • Immobilized Bafisontamab can bind Human EGFR Protein (ECD, His Tag). The EC50for this effect is 3.76 ng/mL.
  • Immobilized Bafisontamab can bind Human c-MET/HGFR Protein (ECD, His Tag). The EC50 for this effect is 3.28 ng/mL.
  • Flow Cytometry analysis of Hela cells labelling EGFR (red) with Bafisontamab (HY-P99455). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Flow cytometric analysis of 1X106 HT-29 cells labeling MET with Bafisontamab (HY-P99455, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • [(G1 VK-CK-VH-CH1-h-CH2-CH3_L-kappa)_VH-CH1]-dimer