OTUD6A - OTU deubiquitinase 6A Gene
Also Known as DUBA2; HSHIN6
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 139562
Summary
Deubiquitinating Enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. DUBA2 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.[supplied by OMIM, May 2008]
OTUD6A Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_207320.3 | NP_997203.1 | OTU domain-containing protein 6A |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables cysteine-type deubiquitinase activity |
IDA
IDA: Inferred from direct assay
|
23827681 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
32296183 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in protein K11-linked deubiquitination |
IDA
IDA: Inferred from direct assay
|
23827681 | GOA |
| involved in protein K27-linked deubiquitination |
IDA
IDA: Inferred from direct assay
|
23827681 | GOA |
| involved in protein K29-linked deubiquitination |
IDA
IDA: Inferred from direct assay
|
23827681 | GOA |
| involved in protein K33-linked deubiquitination |
IDA
IDA: Inferred from direct assay
|
23827681 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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OTUD6A Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
OTUD6A | Q7L8S5 | DPYSL3 | Homo sapiens | Q14195-2 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | DPYSL3 | Homo sapiens | Q14195-2 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | POM121 | Homo sapiens | Q96HA1-2 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | POM121 | Homo sapiens | Q96HA1-2 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | POM121 | Homo sapiens | Q96HA1-2 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | MYCL | Homo sapiens | P12524-2 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | MYCL | Homo sapiens | P12524-2 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | VPS52 | Homo sapiens | Q8N1B4 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | VPS52 | Homo sapiens | Q8N1B4 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | VPS52 | Homo sapiens | Q8N1B4 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | TRIM7 | Homo sapiens | Q9C029 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | TRIM7 | Homo sapiens | Q9C029 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | TRIM7 | Homo sapiens | Q9C029 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | NUP62 | Homo sapiens | P37198 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | NUP62 | Homo sapiens | P37198 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | DYNLL1 | Homo sapiens | P63167 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | DYNLL1 | Homo sapiens | P63167 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | PDLIM7 | Homo sapiens | Q9NR12 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | PDLIM7 | Homo sapiens | Q9NR12 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | PDLIM7 | Homo sapiens | Q9NR12 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | SSBP1 | Homo sapiens | Q04837 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | SSBP1 | Homo sapiens | Q04837 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | EMX2 | Homo sapiens | Q04743 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | EMX2 | Homo sapiens | Q04743 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | DYNLL2 | Homo sapiens | Q96FJ2 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | DYNLL2 | Homo sapiens | Q96FJ2 | 32296183 | |
|
Intra
|
OTUD6A | Q7L8S5 | DYNLL2 | Homo sapiens | Q96FJ2 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction