2 Results for "

139562

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "139562" in MCE Product Catalog:

Cat. No.: HY-139562
CAS No.: 2314378-09-9
Target:  

FXR

Research Areas:  

Metabolic Disease

BMS-986318 is a potent nonbile acid FXR agonist with EC50s of 53 and 350 nM in the FXR Gal4 and SRC-1 recruitment assays, respectively. BMS-986318 has a suitable ADME profile, and demonstrates efficacy in the mouse bile duct ligation model of liver cholestasis and fibrosis.BMS-986318 can be used for the research of nonalcoholic steatohepatitis .
Cat. No.: HY-P701484
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: OTUD6A; OTU domain-containing protein 6A; DUBA-2
Species:  
Source: