Rack1 - receptor for activated C kinase 1 Gene

Also Known as p205; Gnb2l1; GB-like; Gnb2-rs1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14694

Summary

Enables ion channel inhibitor activity. Involved in negative regulation of hydrogen peroxide-induced neuron death. Acts upstream of or within pigmentation and translation. Located in cytoplasm; dendrite; and neuronal cell body. Is expressed in several structures, including central nervous system; genitourinary system; liver; and spleen. Orthologous to human RACK1 (receptor for activated C kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Rack1 Products (1)

mRNA Protein Name
NM_008143.3 NP_032169.1 receptor of activated protein C kinase 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ion channel inhibitor activity IDA
IDA: Inferred from direct assay
18258429 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15102471 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide IGI
IGI: Inferred from genetic interaction
24947010 MGI
acts upstream of or within pigmentation IMP
IMP: Inferred from mutant phenotype
23212600 MGI
acts upstream of or within translation IMP
IMP: Inferred from mutant phenotype
23212600 MGI
Cellular Component GO Annotation Evidence References Source
located in cell body IDA
IDA: Inferred from direct assay
24947010 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
12826667 MGI
located in dendrite IDA
IDA: Inferred from direct assay
16414032 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
24947010 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
16414032 MGI
part of small ribosomal subunit IDA
IDA: Inferred from direct assay
36517592 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

receptor of activated protein C kinase 1

  • 12-3

  • activated protein kinase C receptor

  • guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 sequence 1

  • guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1

  • guanine nucleotide binding protein related

  • guanine

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P0221C PACAP (1-38) free acid 99.94% Unkown
HY-141891 M435-1279 Inhibitor 98.43% Unkown
HY-N10335 Harringtonolide Inhibitor 98.0% Unkown
HY-162254 EGFR/ACK1-IN-1 Inhibitor 98.19% Unkown
HY-RS11595 RACK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-P0221B PACAP (1-38) free acid TFA / Unkown
HY-P1371 Pseudo RACK1 Agonist / Unkown
HY-P3879 Protein Kinase C (660-673) / Unkown
HY-181165 SB2960 Inhibitor / Unkown
HY-RS16781 Rack1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23221 Rack1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rack1 NCBI NCBI:10399