Haspin - histone H3 associated protein kinase Gene

Mus musculus

Also known as Gsg2

Gene ID: 14841 | Gene type: protein coding

About Haspin

Chromosome 11: 73,026,311-73,029,120 reverse strand.GRCm39:CM001004.3

This gene has 1 transcript (splice variant), 174 orthologues, 4 paralogues and is associated with 1 phenotype.

Summary

Enables ATP binding activity; DNA binding activity; and protein serine/threonine kinase activity. Involved in intracellular signal transduction and protein phosphorylation. Acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle. Located in nucleus. Orthologous to human HASPIN (histone H3 associated protein kinase). [provided by Alliance of Genome Resources, Apr 2022]

Haspin Products(1)

mRNA	Protein	Name
NM_010353.2	NP_034483.1	serine/threonine-protein kinase haspin

Haspin Protein Structure

PKc_like

0
200
400
600
754 a.a.

Protein Preferred Names

Protein Names

serine/threonine-protein kinase haspin

germ cell associated 2, haspin	germ cell-specific gene 2 protein
haploid germ cell-specific nuclear protein kinase

Related Agents

Pre-clinical Phase

Bioactive Molecules (14)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15424	5-Iodotubercidin	Inhibitor	99.64%	Unkown
HY-15217	CHR-6494	Inhibitor	98.07%	Unkown
HY-13455	LDN-192960	Inhibitor	99.56%	Unkown
HY-110320	LDN-209929 dihydrochloride	Inhibitor	≥99.0%	Unkown
HY-13455A	LDN-192960 hydrochloride	Inhibitor	99.78%	Unkown
HY-146636	Haspin-IN-3	Inhibitor	98.14%	Unkown
HY-110350	CHR-6494 TFA	Inhibitor	/	Unkown
HY-146586	Haspin-IN-1	Inhibitor	/	Unkown
HY-146587	Haspin-IN-2	Inhibitor	/	Unkown
HY-155341	HSK205	Inhibitor	/	Unkown
HY-RS06009	HASPIN Human Pre-designed siRNA Set A		/	Unkown
HY-RS06010	Haspin Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS06011	Haspin Rat Pre-designed siRNA Set A		/	Unkown
HY-100368	MELK-8a		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Haspin	NCBI	NCBI:83903

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