2. Gene
  3. EEF1G - eukaryotic translation elongation factor 1 gamma Gene

EEF1G - eukaryotic translation elongation factor 1 gamma Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as EF1G; GIG35

Gene ID: 1937 | Gene type: protein coding

About EEF1G

Cytogenetic location: 11q12.3 Genomic coordinates (GRCh38): 11:62,559,596-62,573,891 (from NCBI)

This gene has 4 transcripts (splice variants), 235 orthologues and 14 paralogues. Ubiquitous expression in ovary (RPKM 1189.4), lymph node (RPKM 694.2) and 25 other tissues.

Summary

This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases. [provided by RefSeq, Jul 2008]

EEF1G Products(1)

mRNA Protein Name
NM_001404.5 NP_001395.1 elongation factor 1-gamma

EEF1G Protein Structure

GST_N

GST_N: Glutathione S-transferase, N-terminal domain (3 - 80)

GST_C

GST_C: Glutathione S-transferase, C-terminal domain (108 - 198)

EF1G

EF1G: Elongation factor 1 gamma, conserved domain (275 - 381)

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  • 437 a.a.
Protein Preferred Names Protein Names

elongation factor 1-gamma

EF-1-gamma

Related Diseases

Diseases Alias
Pontiac Fever
Podoconiosis

PDCOS

Podoconiosis, Susceptibility To

Nonfilarial Elephantiasis Of Lower Legs

Nonfilarial Elephantiasis Of Lower Legs, Susceptibility To

Endemic Nonfilarial Elephantiasis

Endemic Nonfilarial Elephantiasis, Susceptibility To

Lymphostatic Verrucosis

Lymphostatic Verrucosis, Susceptibility To

Elephantiasis

Endemic Non-Filarial Elephantiasis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04179 EEF1G Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus EEF1G MGD MGI:1914410
Rattus norvegicus EEF1G RGD RGD:1302939
Bos taurus EEF1G VGNC VGNC:28334
Felis catus EEF1G VGNC VGNC:81197