2 Results for "

196477

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "196477" in MCE Product Catalog:

Cat. No.: HY-13550
CAS No.: 64862-96-0
Synonyms: NSC 196473; NSC 290813
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Ametantrone (NSC 196473) is an antitumor agent that intercalates into DNA and induces topoisomerase II (TOP2)-mediated DNA break .
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Cat. No.: HY-13550A
CAS No.: 70711-40-9
Synonyms: NSC 196473 acetate; NSC 290813 acetate
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Ametantrone acetate (NSC 196473 acetate) is an antineoplastic drug with topoisomerase II inhibitory activity. Ametantrone acetate causes covalent cross-linking of DNA. The pharmacokinetic profile of Ametantrone acetate has been confirmed in clinical trials, and its elimination pathway in the body indicates the existence of a major metabolic pathway .
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