CCR1 antagonist 12
CCR1 antagonist 12 (Compound 12) is an antagonist for CCR1 with IC50 of 3 nM for human CCR1. CCR1 antagonist 12 inhibits CCL3-induced transwell chemotaxis with an IC50 of 0.009 µM. CCR1 antagonist 12 exhibits good pharmacokinetic characters in rats model.
For research use only. We do not sell to patients.
- CAS No.: 921208-19-7
- Formula: C25H27ClFN3O4
- Molecular Weight:487.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CCR1 3 nM (IC50) |
Chemical Information
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CAS No. 921208-19-7
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Molecular Weight 487.95
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Formula C25H27ClFN3O4
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SMILES
CC(NC1=CC(Cl)=C(OC)C=C1/C=C/C(N2CC3COCC(N3CC4=CC=C(F)C=C4)C2)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)