Sts - steroid sulfatase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24800

Summary

Enables steryl-sulfatase activity. Involved in several processes, including response to estrogen; response to pH; and response to peptide hormone. Located in endoplasmic reticulum membrane and nuclear envelope. Is integral component of membrane. Biomarker of cryptorchidism and hypertension. Human ortholog(s) of this gene implicated in X-linked ichthyosis. Orthologous to human STS (Steroid Sulfatase). [provided by Alliance of Genome Resources, Apr 2022]

Sts Products (1)

mRNA Protein Name
NM_012661.2 NP_036793.2 steryl-sulfatase precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables steryl-sulfatase activity IDA
IDA: Inferred from direct assay
8662223 RGD
Biological Process GO Annotation Evidence References Source
involved in learning or memory IMP
IMP: Inferred from mutant phenotype
10821934 RGD
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
17268815 RGD
involved in response to estrogen IDA
IDA: Inferred from direct assay
2965775 RGD
involved in response to organic cyclic compound IDA
IDA: Inferred from direct assay
11282279 RGD
involved in response to pH IDA
IDA: Inferred from direct assay
6586719 RGD
involved in response to peptide hormone IDA
IDA: Inferred from direct assay
2779233 RGD
involved in skin development IEP
IEP: Inferred from expression pattern
9182813 RGD
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
2703703 RGD
located in nuclear envelope IDA
IDA: Inferred from direct assay
2703703 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

steryl-sulfatase

  • ASC

  • arylsulfatase C

  • steroid sulfatase (microsomal), isozyme S

  • steryl-sulfate sulfohydrolase

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0084 Dienogest Agonist 99.93% Unkown

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-15141 Staurosporine 99.77% Phase 4

Pre-clinical Phase

Bioactive Molecules (28)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W062700 STS-E412 Activator 99.72% Unkown
HY-15141G Staurosporine (GMP) Inhibitor / Unkown
HY-175869 Ferroptosis-IN-22 Inhibitor 99.97% Unkown
HY-14585 Estrone O-sulfamate Inhibitor 99.99% Unkown
HY-112944A CMP-SiaNAz sodium Substrate 93.0% Unkown
HY-123773 SR-16157 / Unkown
HY-123868 KW-2581 Inhibitor / Unkown
HY-150542 Steroid sulfatase-IN-2 Inhibitor / Unkown
HY-150543 Steroid sulfatase-IN-3 Inhibitor / Unkown
HY-151200 Steroid sulfatase-IN-4 Inhibitor / Unkown
HY-151201 Steroid sulfatase/17β-HSD1-IN-3 Inhibitor / Unkown
HY-151202 Steroid sulfatase/17β-HSD1-IN-4 Inhibitor / Unkown
HY-155010 Steroid sulfatase/17β-HSD1-IN-5 Inhibitor / Unkown
HY-155233 Steroid sulfatase-IN-5 Inhibitor / Unkown
HY-155234 Steroid sulfatase-IN-6 Inhibitor / Unkown
HY-155235 Steroid sulfatase-IN-7 Inhibitor / Unkown
HY-156511 ETC-168 Inhibitor / Unkown
HY-156902 Steroid sulfatase-IN-8 Inhibitor / Unkown
HY-172605 Steroid sulfatase-IN-9 Inhibitor / Unkown
HY-B0084S Dienogest-d4 / Unkown
HY-B0084S1 Dienogest-d5 / Unkown
HY-B0084S2 Dienogest-d6 99.92% Unkown
HY-B0084S4 Dienogest-13C,15N,d4 Agonist / Unkown
HY-RS13969 STS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-181408 Steroid sulfatase-IN-11 Inhibitor / Unkown
HY-B0084S3 Dienogest-13C2,15N Agonist / Unkown
HY-RS16525 Sts Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22956 Sts Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sts NCBI NCBI:412