1. Gene
  2. Ddr1 - discoidin domain receptor tyrosine kinase 1 Gene

Ddr1 - discoidin domain receptor tyrosine kinase 1 Gene

Rattus norvegicus

Also known as Cak; Drd1; PTK3D

Gene ID: 25678 | Gene type: protein coding

About Ddr1

Primary_assembly 20: 3,044,320-3,064,468 forward strand.mRatBN7.2:CM026993.1

This gene has 2 transcripts (splice variants), 196 orthologues, 54 paralogues and is associated with 31 phenotypes. Biased expression in Kidney (RPKM 22.8), Brain (RPKM 117.8) and 8 other tissues.

Summary

Predicted to enable collagen binding activity and protein tyrosine kinase collagen receptor activity. Involved in animal organ regeneration and skin development. Located in basolateral plasma membrane; brush border; and cytoplasm. Biomarker of congestive heart failure. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human DDR1 (Discoidin Domain Receptor tyrosine kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ddr1 Products(2)

mRNA Protein Name
NM_013137.2 NP_037269.2 epithelial discoidin domain-containing receptor 1 precursor
NM_001166022.1 NP_001159494.1 epithelial discoidin domain-containing receptor 1 precursor

Ddr1 Protein Structure

FA58C

FA58C: cd00057 (57 - 184)

PTKc_DDR1

PTKc_DDR1: cd05096 (600 - 903)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 910 a.a.
Protein Preferred Names Protein Names

epithelial discoidin domain-containing receptor 1

CD167 antigen-like family member A

cell adhesion kinase

discoidin domain receptor family, member 1

discoidin receptor tyrosine kinase

epithelial discoidin domain receptor 1

neurotrophic tyrosine kinase receptor type 4

protein-tyrosine kinase 3

protein-tyrosine kinase PTK-3

tyrosine kinase DDR

tyrosine-protein kinase CAK

Recombinant Ddr1 Proteins

Cat. No. Product Name Accession Purity
HY-P75299 DDR1 Protein, Rat (HEK293, His) Q6MG19 (D22-T413) ≥95%
HY-P75300 DDR1 Protein, Rat (HEK293, hFc) Q6MG19 (M1-T413) ≥95%

Orthologs Information

Species Symbol Source ID
Homo sapiens Ddr1 NCBI NCBI:780
Mus musculus Ddr1 NCBI NCBI:12305