CENPQ - centromere protein Q Gene

Homo sapiens

Also known as CENP-Q; C6orf139

Gene ID: 55166 | Gene type: protein coding

About CENPQ

Cytogenetic location: 6p12.3 Genomic coordinates (GRCh38): 6:49,463,370-49,493,107 (from NCBI)

This gene has 1 transcript (splice variant) and 170 orthologues. Ubiquitous expression in testis (RPKM 3.5), brain (RPKM 3.4) and 25 other tissues.

Summary

CENPQ is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM, Mar 2008]

CENPQ Products(1)

mRNA	Protein	Name
NM_018132.4	NP_060602.2	centromere protein Q

CENPQ Protein Structure

CENP-Q

0
100
200
268 a.a.

Protein Preferred Names

Protein Names

centromere protein Q

Related Diseases

Diseases

Alias

Crest Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02489	CENPQ Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CENPQ	VGNC	VGNC:60760
Macaca mulatta	CENPQ	VGNC	VGNC:81053
Bos taurus	CENPQ	VGNC	VGNC:27184
Rattus norvegicus	CENPQ	RGD	RGD:1359451
Mus musculus	CENPQ	MGD	MGI:1933744
Canis familiaris	CENPQ	VGNC	VGNC:39112

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