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STAMBPL1 - STAM binding protein like 1 Gene

Also Known as AMSH-FP; AMSH-LP; ALMalpha; bA399O19.2

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 57559

About STAMBPL1

Cytogenetic location: 10q23.31 Genomic coordinates (GRCh38): 10:88,880,245-88,923,487 (from NCBI)

This gene has 6 transcripts (splice variants), 206 orthologues and 1 paralogue. Broad expression in adrenal (RPKM 7.5), testis (RPKM 6.2) and 22 other tissues.

Summary

Predicted to enable Lys63-specific Deubiquitinase activity and thiol-dependent Deubiquitinase. Predicted to be involved in protein K63-linked deubiquitination. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

STAMBPL1 Products (1)

mRNA	Protein	Name
NM_020799.4	NP_065850.1	AMSH-like protease

STAMBPL1 Protein Structure

USP8_dimer

JAB

0
100
200
300
400
436 a.a.

Protein Preferred Names	Protein Names
AMSH-like protease	associated molecule with the SH3 domain of STAM (AMSH) - Family Protein

STAMBPL1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	STAMBPL1	Q96FJ0	MAGEA6	Homo sapiens	P43360	Y2H Prey Pooling	32296183
Intra	STAMBPL1	Q96FJ0	MAGEA6	Homo sapiens	P43360	Y2H Array	25416956
Intra	STAMBPL1	Q96FJ0	MAGEA6	Homo sapiens	P43360	Y2H Array	32296183
Intra	STAMBPL1	Q96FJ0	MAGEA6	Homo sapiens	P43360	Y2H Prey Pooling	25416956
Intra	STAMBPL1	Q96FJ0	REL	Homo sapiens	Q04864-2	Y2H Prey Pooling	32296183
Intra	STAMBPL1	Q96FJ0	GNPTAB	Homo sapiens	Q3T906	Y2H Array	25416956
Intra	STAMBPL1	Q96FJ0	MORN5	Homo sapiens	Q5VZ52	Y2H Prey Pooling	32296183
Intra	STAMBPL1	Q96FJ0	MORN5	Homo sapiens	Q5VZ52	Y2H Array	32296183
Intra	STAMBPL1	Q96FJ0	GCSAML	Homo sapiens	Q5JQS6	Y2H Array	32296183
Intra	STAMBPL1	Q96FJ0	GCSAML	Homo sapiens	Q5JQS6	Y2H Prey Pooling	32296183
Intra	STAMBPL1	Q96FJ0	SF3B5	Homo sapiens	Q9BWJ5	Y2H Prey Pooling	32296183
Intra	STAMBPL1	Q96FJ0	SF3B5	Homo sapiens	Q9BWJ5	Validated Y2H	32296183
Intra	STAMBPL1	Q96FJ0	SF3B5	Homo sapiens	Q9BWJ5	Y2H Array	32296183
Intra	STAMBPL1	Q96FJ0	PNMA1	Homo sapiens	Q8ND90	Validated Y2H	25416956
Intra	STAMBPL1	Q96FJ0	PNMA1	Homo sapiens	Q8ND90	Y2H Array	25416956
Intra	STAMBPL1	Q96FJ0	ZRANB1	Homo sapiens	Q9UGI0	Y2H Prey Pooling	32296183
Intra	STAMBPL1	Q96FJ0	ZRANB1	Homo sapiens	Q9UGI0	Validated Y2H	32296183
Intra	STAMBPL1	Q96FJ0	ZRANB1	Homo sapiens	Q9UGI0	Y2H Array	32296183
Intra	STAMBPL1	Q96FJ0	TCF4	Homo sapiens	P15884	Y2H Prey Pooling	25416956
Intra	STAMBPL1	Q96FJ0	TCF4	Homo sapiens	P15884	Y2H Array	25416956
Intra	STAMBPL1	Q96FJ0	TCF4	Homo sapiens	P15884	Validated Y2H	25416956
Intra	STAMBPL1	Q96FJ0	MAGEA3	Homo sapiens	P43357	Anti Tag CoIP	33961781
Intra	STAMBPL1	Q96FJ0	MAGEA3	Homo sapiens	P43357	Y2H Prey Pooling	32296183
Intra	STAMBPL1	Q96FJ0	MAGEA3	Homo sapiens	P43357	Y2H Array	32296183
Intra	STAMBPL1	Q96FJ0	ZNF835	Homo sapiens	Q9Y2P0	Validated Y2H	32296183
Intra	STAMBPL1	Q96FJ0	ZNF835	Homo sapiens	Q9Y2P0	Y2H Array	32296183
Intra	STAMBPL1	Q96FJ0	ZNF835	Homo sapiens	Q9Y2P0	Y2H Prey Pooling	32296183
Intra	STAMBPL1	Q96FJ0	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Prey Pooling	32296183
Intra	STAMBPL1	Q96FJ0	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Array	32296183
Intra	STAMBPL1	Q96FJ0	GOLGA2	Homo sapiens	Q08379	Validated Y2H	25416956
Intra	STAMBPL1	Q96FJ0	INCA1	Homo sapiens	Q0VD86	Y2H Array	25416956
Intra	STAMBPL1	Q96FJ0	INCA1	Homo sapiens	Q0VD86	Y2H Prey Pooling	25416956
Intra	STAMBPL1	Q96FJ0	TRIM27	Homo sapiens	P14373	Y2H Array	25416956
Intra	STAMBPL1	Q96FJ0	TRIM27	Homo sapiens	P14373	Y2H Array	32296183
Intra	STAMBPL1	Q96FJ0	TRIM27	Homo sapiens	P14373	Y2H Prey Pooling	32296183
Intra	STAMBPL1	Q96FJ0	CEP72	Homo sapiens	Q9P209	Y2H Prey Pooling	25416956
Intra	STAMBPL1	Q96FJ0	CEP72	Homo sapiens	Q9P209	Validated Y2H	25416956
Intra	STAMBPL1	Q96FJ0	CEP72	Homo sapiens	Q9P209	Y2H Prey Pooling	32296183
Intra	STAMBPL1	Q96FJ0	CEP72	Homo sapiens	Q9P209	Validated Y2H	32296183
Intra	STAMBPL1	Q96FJ0	CEP72	Homo sapiens	Q9P209	Y2H Array	25416956
Intra	STAMBPL1	Q96FJ0	CEP72	Homo sapiens	Q9P209	Y2H Array	32296183
Intra	STAMBPL1	Q96FJ0	CALCOCO2	Homo sapiens	Q13137	Y2H Array	32296183
Intra	STAMBPL1	Q96FJ0	CALCOCO2	Homo sapiens	Q13137	Y2H Prey Pooling	32296183
Intra	STAMBPL1	Q96FJ0	PLEKHF2	Homo sapiens	Q9H8W4	Validated Y2H	32296183
Intra	STAMBPL1	Q96FJ0	PLEKHF2	Homo sapiens	Q9H8W4	Y2H Array	32296183
Intra	STAMBPL1	Q96FJ0	PLEKHF2	Homo sapiens	Q9H8W4	Y2H Prey Pooling	32296183
Intra	STAMBPL1	Q96FJ0	IKZF3	Homo sapiens	Q9UKT9	Y2H Prey Pooling	25416956
Intra	STAMBPL1	Q96FJ0	IKZF3	Homo sapiens	Q9UKT9	Validated Y2H	25416956
Intra	STAMBPL1	Q96FJ0	RAB2A	Homo sapiens	P61019	Y2H Array	32296183
Intra	STAMBPL1	Q96FJ0	RAB2A	Homo sapiens	P61019	Validated Y2H	25416956
Intra	STAMBPL1	Q96FJ0	RAB2A	Homo sapiens	P61019	Y2H Prey Pooling	32296183
Intra	STAMBPL1	Q96FJ0	RAB2A	Homo sapiens	P61019	Y2H Array	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Hermansky-Pudlak Syndrome 3	HPS3 Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Delta Storage Pool Disease Hermansky-Pudlak Syndrome, Type 3 Platelet Storage Pool Deficiency Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells
Camptodactyly-Arthropathy-Coxa Vara-Pericarditis Syndrome	Jacobs Syndrome Arthropathy-Camptodactyly Syndrome Pericarditis-Arthropathy-Camptodactyly Syndrome Xyy Syndrome Pac Syndrome Cacp Syndrome CACP Fibrosing Serositis, Familial Camptodactyly-Arthropathy-Pericarditis Syndrome Cap Syndrome 47, Xyy Syndrome 47,Xyy Syndrome Double Y Syndrome Camptodactyly-Arthropathy-Coxa-Vara-Pericarditis Syndrome Hypertrophic Synovitis, Congenital Familial Congenital Familial Hypertrophic Synovitis Xyy Karyotype Y Disomy Yy Syndrome Familial Fibrosing Serositis Disomy Y Double Y Camptodactyly Arthropathy Coxa Vara Pericarditis Syndrome Arthropathy Camptodactyly Syndrome Camptodactyly Arthropathy Pericarditis Syndrome Pericarditis Arthropathy Camptodactyly Syndrome Jacob'S Syndrome 47,Xyy Cdags Syndrome
Autosomal Dominant Cerebellar Ataxia	Spinocerebellar Ataxia Adca Pierre Marie Cerebellar Ataxia Ataxia, Spinocerebellar Sca Autosomal Dominant Spinocerebellar Ataxia Spinocerebellar Ataxias

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13872	STAMBPL1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22077	Stambpl1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS28595	Stambpl1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	STAMBPL1	MGD	MGI:1923880
Bos taurus	STAMBPL1	VGNC	VGNC:35357
Felis catus	STAMBPL1	VGNC	VGNC:65748
Rattus norvegicus	STAMBPL1	RGD	RGD:1583011
Macaca mulatta	STAMBPL1	VGNC	VGNC:77982
Canis familiaris	STAMBPL1	VGNC	VGNC:46877
Others	STAMBPL1	NCBI